Protein: CRBA4
Beta-crystallin A4 (Beta-A4 crystallin)

Gene: CRBA4, CRYBA4
Organism: Homo sapiens
Interactions: 41
UniProt ID: P53673

Gene Ontology (top 5):
GO:0002088 - lens development in camera-type eye
GO:0005212 - structural constituent of eye lens
GO:0007601 - visual perception
GO:0042802 - identical protein binding
GO:0043010 - camera-type eye development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

922374

CRBB1
Beta-crystallin B1

3

15

Small-scale

0.845

High

922373

CRBA4
Beta-crystallin A4

1

14

Small-scale

0.756

High

847802

CRBB2
Beta-crystallin B2

1

16

Small-scale

0.590

High

690010

CRBB3
Beta-crystallin B3

1

16

High-throughput

0.575

High

922375

EMAL5
Echinoderm microtubule-associated protein-like 5

2

2

High-throughput

0.574

High

922379

FOXF2
Forkhead box protein F2

2

1

High-throughput

0.574

High

922381

CUL4A
Cullin-4A

2

2

High-throughput

0.574

High

922382

CUL4B
Cullin-4B

2

2

High-throughput

0.574

High

922388

RICTR
Rapamycin-insensitive companion of mTOR

2

1

High-throughput

0.574

High

922393

DDB2
DNA damage-binding protein 2

2

1

High-throughput

0.574

High

922378

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

1

0

High-throughput

0.549

High

72407

MI4GD
MIF4G domain-containing protein

1

1

High-throughput

0.523

High

922385

TRIP6
Thyroid receptor-interacting protein 6

1

3

High-throughput

0.523

High

922386

FHL5
Four and a half LIM domains protein 5

1

4

High-throughput

0.523

High

922390

CCD33
Coiled-coil domain-containing protein 33

1

1

High-throughput

0.523

High

158983

ZN195
Zinc finger protein 195

1

1

High-throughput

0.489

High

161703

APAF
Apoptotic protease-activating factor 1

1

2

High-throughput

0.489

High

331727

MTMR5
Myotubularin-related protein 5

1

1

High-throughput

0.489

High

894459

PPOX
Protoporphyrinogen oxidase

1

1

High-throughput

0.489

High

922397

TF7L2
Transcription factor 7-like 2

1

1

High-throughput

0.489

High

922398

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.489

High

384387

CRYAA
Alpha-crystallin A chain

1

13

Small-scale

0.457

High

922389

PRR22
Proline-rich protein 22

1

1

High-throughput

0.439

High

922384

Q149M6
Exophilin 5

1

1

High-throughput

0.437

High

922391

EXPH5
Exophilin-5

1

1

High-throughput

0.407

High

922392

CEP76
Centrosomal protein of 76 kDa

3

0

High-throughput

0.356

High

389598

RET4
Retinol-binding protein 4

2

0

High-throughput

0.328

High

507123

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

0

High-throughput

0.328

High

922376

ZO1
Tight junction protein 1

2

0

High-throughput

0.328

High

922395

CSN8
COP9 signalosome complex subunit 8

2

0

High-throughput

0.313

High

286634

STX11
Syntaxin-11

1

0

High-throughput

0.299

High

466645

GLI1
Zinc finger protein GLI1

1

0

High-throughput

0.299

High

922387

CA094
Uncharacterized protein C1orf94

1

0

High-throughput

0.299

High

922400

IKZF3
Zinc finger protein Aiolos

1

0

High-throughput

0.299

High

922377

TF3C1
General transcription factor 3C polypeptide 1

1

0

High-throughput

0.279

Low

922380

ORC2
Origin recognition complex subunit 2

1

0

High-throughput

0.279

Low

922394

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

0

High-throughput

0.279

Low

922399

MKS1
Tectonic-like complex member MKS1

1

0

High-throughput

0.279

Low

922383

PEBB
Core-binding factor subunit beta

1

0

High-throughput

0.232

Low

922396

CSN4
COP9 signalosome complex subunit 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025