HitPredict

Interactor 1: CRBA2 (P53672)
Beta-crystallin A2 (Beta-A2 crystallin)
Gene: CRYBA2

Interactor 2: CRBB1 (P53674)
Beta-crystallin B1 (Beta-B1 crystallin)
Gene: CRYBB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	17662718
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Crystall~Crystall
Common GO terms	GO:0002088 - lens development in camera-type eye GO:0005212 - structural constituent of eye lens GO:0007601 - visual perception
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 197 Hs			1 252
+	Hs
		437458 CRBA1_HUMAN (5-197): 1.12e-91: 268: 53.61		CRBB1_HUMAN (15-252): 1.41e-133: 378: 100.00
+	Hs
		922374 CRBA4_HUMAN (1-197): 5.92e-89: 261: 52.28		CRBB1_HUMAN (15-252): 1.41e-133: 378: 100.00
+	Hs
		922401 CRBB1_HUMAN (9-196): 1.34e-76: 231: 48.15		CRBB1_HUMAN (15-252): 1.41e-133: 378: 100.00
+	Hs
		437454 CRBA1_HUMAN (5-197): 1.12e-91: 268: 53.61		CRBA1_HUMAN (43-234): 1.02e-87: 261: 47.32
+	Hs
		922373 CRBA4_HUMAN (1-197): 5.92e-89: 261: 52.28		CRBA4_HUMAN (51-234): 2.32e-81: 244: 42.78
+	Hs
		437457 CRBA1_HUMAN (5-197): 1.12e-91: 268: 53.61		CRBB2_HUMAN (43-143): 1.31e-19: 85.4: 23.30
+	Hs
		437455 CRBA1_HUMAN (5-197): 1.12e-91: 268: 53.61		CRBB3_HUMAN (48-143): 5.03e-19: 84.3: 33.67
+	Hs
		847801 CRBA2_HUMAN (14-197): 8.34e-90: 263: 100.00		CRBB2_HUMAN (43-143): 1.31e-19: 85.4: 23.30
+	Hs
		690009 CRBA2_HUMAN (14-197): 8.34e-90: 263: 100.00		CRBB3_HUMAN (48-143): 5.03e-19: 84.3: 33.67
+	Hs
		847802 CRBA4_HUMAN (1-197): 5.92e-89: 261: 52.28		CRBB2_HUMAN (43-143): 1.31e-19: 85.4: 23.30
+	Hs
		690010 CRBA4_HUMAN (1-197): 5.92e-89: 261: 52.28		CRBB3_HUMAN (48-143): 5.03e-19: 84.3: 33.67
+	Hs
		690011 CRBB1_HUMAN (9-196): 1.34e-76: 231: 48.15		CRBB3_HUMAN (48-143): 5.03e-19: 84.3: 33.67
+	Bt
		385026 CRBB2_BOVIN (2-196): 3.24e-74: 224: 39.29		CRBB3_BOVIN (146-232): 5e-20: 87: 32.58
+	Bt
		385025 CRBB2_BOVIN (2-196): 3.24e-74: 224: 39.29		CRBB2_BOVIN (43-123): 9.29e-19: 83.5: 25.30
+	Mm
		977117 CRBB2_MOUSE (2-196): 1.36e-73: 222: 38.78		CRBB2_MOUSE (43-143): 3.07e-19: 84.6: 23.30
+	Hs
		847800 CRBB2_HUMAN (2-196): 1.05e-72: 220: 37.76		CRBB2_HUMAN (43-143): 1.31e-19: 85.4: 23.30
+	Hs
		456052 CRBB2_HUMAN (2-196): 1.05e-72: 220: 37.76		CRGC_HUMAN (48-142): 1.69e-19: 84.6: 30.61