HitPredict

Interactor 1: IRAK1 (P51617)
Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)
Gene: IRAK1

Interactor 2: UN45A (Q9H3U1)
Protein unc-45 homolog A (Unc-45A) (GCUNC-45) (Smooth muscle cell-associated protein 1) (SMAP-1)
Gene: UNC45A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 712 Hs			1 944
+	Hs
		848483 IRAK1_HUMAN (1-712): 0: 597: 100.00		RPAP3_HUMAN (15-343): 5.32e-41: 163: 17.06
+	Hs
		848331 IRAK1_HUMAN (1-712): 0: 597: 100.00		PPP5_HUMAN (10-180): 3.77e-39: 154: 23.98
+	Hs
		848508 IRAK1_HUMAN (1-712): 0: 597: 100.00		CHIP_HUMAN (8-159): 1.54e-35: 139: 29.30
+	Hs
		684539 IRAK1_HUMAN (1-712): 0: 597: 100.00		STIP1_HUMAN (4-228): 9.18e-17: 86.8: 15.32
+	Hs
		297043 IRAK1_HUMAN (1-712): 0: 597: 100.00		TOM70_HUMAN (12-220): 4.6e-09: 62.2: 13.08