Interactor 1: IRAK1 (P51617)
Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)
Gene: IRAK1
Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 0.60 | 0.770 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28882891, 30872404, 11518704, 10920205, 11259596, 35785771, 11287640, 21220427, 20043910, 19716405, 14625308, 12242293, 17785851, 19166926, 16951688, 16024789, 23244239, 23381138, 18347055, 31921110 and 21 others
more... |
| Identification Methods | affinity chromatography technology, two hybrid, enzymatic study, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0002755 - MyD88-dependent toll-like receptor signaling pathway GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005811 - lipid droplet GO:0005829 - cytosol and 15 others more... |
| Homologous interactions | 10 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
