Interactor 1: CNTF (P51642)
Ciliary neurotrophic factor (CNTF)
Gene: CNTF

Interactor 2: IL6RB (Q00560)
Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130)
Gene: Il6st

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 15051883
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005127 - ciliary neurotrophic factor receptor binding
GO:0005138 - interleukin-6 receptor binding
GO:0008284 - positive regulation of cell population proliferation
GO:0042531 - positive regulation of tyrosine phosphorylation of STAT protein
GO:0043025 - neuronal cell body
and 1 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 198
Mm

1 917
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm

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Last updated: 15 Jul 2024