Interactor 1: CLCN5 (P51795)
H(+)/Cl(-) exchange transporter 5 (Chloride channel protein 5) (ClC-5) (Chloride transporter ClC-5)
Gene: CLCN5

Interactor 2: CLCN5 (P51795)
H(+)/Cl(-) exchange transporter 5 (Chloride channel protein 5) (ClC-5) (Chloride transporter ClC-5)
Gene: CLCN5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 17195847
Identification Methods x-ray crystallography, cosedimentation in solution
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CBS~CBS, CBS~Voltage_CLC, Voltage_CLC~Voltage_CLC
Common GO terms GO:0000139 - Golgi membrane
GO:0003014 - renal system process
GO:0005247 - voltage-gated chloride channel activity
GO:0005524 - ATP binding
GO:0005765 - lysosomal membrane
and 12 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 816
Hs

1 816
+ Hs
+ Hs
+ Gg
+ Hs
+ Ec

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Last updated: 15 Jul 2024