HitPredict

Interactor 1: VAMP7 (P51809)
Vesicle-associated membrane protein 7 (VAMP-7) (Synaptobrevin-like protein 1) (Tetanus-insensitive VAMP) (Ti-VAMP)
Gene: VAMP7

Interactor 2: SNAG (Q99747)
Gamma-soluble NSF attachment protein (SNAP-gamma) (N-ethylmaleimide-sensitive factor attachment protein gamma)
Gene: NAPG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNAP~Synaptobrevin
Common GO terms	GO:0005765 - lysosomal membrane GO:0031201 - SNARE complex GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 220 Hs			1 312
+	Hs
		850546 VAMP7_HUMAN (1-220): 3.87e-90: 266: 100.00		SNAA_HUMAN (22-275): 5.22e-67: 213: 20.93
+	Dm
		1178116 Q7JYX5_DROME (1-218): 3.74e-85: 253: 52.29		Q9U6R9_DROME (1-312): 3.86e-71: 224: 38.14
+	Zm
		31296 A0A1D6KH00_MAIZE (2-211): 1.02e-87: 273: 33.02		A0A1D6PZ82_MAIZE (6-262): 1.94e-62: 203: 22.22
+	Dm
		1095560 Q7JYX5_DROME (1-218): 3.74e-85: 253: 52.29		SNAP_DROME (6-279): 1.99e-65: 209: 17.96
+	Hs
		263338 SC22B_HUMAN (23-206): 4.4e-59: 186: 22.16		SNAG_HUMAN (1-312): 3.66e-87: 265: 100.00
+	Dm
		1178122 Q7JYX5_DROME (1-218): 3.74e-85: 253: 52.29		Q9VH25_DROME (1-290): 3.1e-59: 193: 29.66
+	Hs
		180923 YKT6_HUMAN (23-179): 3.99e-55: 176: 23.42		SNAG_HUMAN (1-312): 3.66e-87: 265: 100.00
+	Hs
		263203 SC22B_HUMAN (23-206): 4.4e-59: 186: 22.16		SNAA_HUMAN (22-275): 5.22e-67: 213: 20.93
+	Dm
		115822 M9PGI6_DROME (24-204): 2.11e-53: 172: 26.23		Q9U6R9_DROME (1-312): 3.86e-71: 224: 38.14
+	Dm
		1353755 Q9W3M8_DROME (5-179): 4.42e-51: 165: 21.02		Q9U6R9_DROME (1-312): 3.86e-71: 224: 38.14
+	Hs
		180842 YKT6_HUMAN (23-179): 3.99e-55: 176: 23.42		SNAA_HUMAN (22-275): 5.22e-67: 213: 20.93
+	Dm
		115802 M9PGI6_DROME (24-204): 2.11e-53: 172: 26.23		SNAP_DROME (6-279): 1.99e-65: 209: 17.96
+	Dm
		1095592 Q9W3M8_DROME (5-179): 4.42e-51: 165: 21.02		SNAP_DROME (6-279): 1.99e-65: 209: 17.96
+	Dm
		115828 M9PGI6_DROME (24-204): 2.11e-53: 172: 26.23		Q9VH25_DROME (1-290): 3.1e-59: 193: 29.66
+	Dm
		1366632 Q9W3M8_DROME (5-179): 4.42e-51: 165: 21.02		Q9VH25_DROME (1-290): 3.1e-59: 193: 29.66
+	Sc
		696563 YKT6_YEAST (5-179): 3.71e-52: 168: 22.73		SEC17_YEAST (6-276): 1.43e-56: 186: 20.14
+	Sc
		605825 SEC22_YEAST (37-206): 4.98e-49: 161: 20.93		SEC17_YEAST (6-276): 1.43e-56: 186: 20.14
+	Dm
		577238 SYB_DROME (99-215): 1.35e-32: 116: 26.50		Q9U6R9_DROME (1-312): 3.86e-71: 224: 38.14
+	Dm
		577215 SYB_DROME (99-215): 1.35e-32: 116: 26.50		SNAP_DROME (6-279): 1.99e-65: 209: 17.96
+	Sc
		696608 NYV1_YEAST (36-208): 2.42e-36: 129: 20.21		SEC17_YEAST (6-276): 1.43e-56: 186: 20.14