HitPredict

Interactor 1: GNAO (P51875)
Guanine nucleotide-binding protein G(o) subunit alpha
Gene: goa-1

Interactor 2: Q19955 (Q19955)
Tetratricopeptide repeat protein 28
Gene: ags-3

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.842

Property	Details
Experiments	14704431, unassigned1274, 18629017
Identification Methods	two hybrid, mammalian protein protein interaction trap, pull down, two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	G-alpha~GoLoco
Common GO terms	GO:0005938 - cell cortex GO:0060259 - regulation of feeding behavior
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 354 Ce			1 579
+	Mm
		579655 GNAO_MOUSE (1-354): 2.66e-172: 484: 81.64		GPSM2_MOUSE (2-513): 4.87e-18: 90.1: 14.37
+	Hs
		926669 GNAI1_HUMAN (1-354): 3.13e-172: 484: 69.86		GPSM2_HUMAN (2-144): 1.42e-15: 82: 23.45
+	Hs
		926692 GNAI1_HUMAN (1-354): 3.13e-172: 484: 69.86		GPSM1_HUMAN (2-152): 4.08e-15: 80.4: 28.11
+	Hs
		391380 GNAI2_HUMAN (1-354): 1.57e-171: 482: 68.17		GPSM2_HUMAN (2-144): 1.42e-15: 82: 23.45
+	Hs
		444714 GNAI3_HUMAN (1-354): 2.32e-169: 477: 69.86		GPSM2_HUMAN (2-144): 1.42e-15: 82: 23.45
+	Hs
		444752 GNAI3_HUMAN (1-354): 2.32e-169: 477: 69.86		GPSM1_HUMAN (2-152): 4.08e-15: 80.4: 28.11
+	Hs
		926693 GNAI1_HUMAN (1-354): 3.13e-172: 484: 69.86		PCP2_HUMAN (408-510): 7.94e-10: 59.1: 29.25
+	Hs
		391427 GNAI2_HUMAN (1-354): 1.57e-171: 482: 68.17		PCP2_HUMAN (408-510): 7.94e-10: 59.1: 29.25
+	Dm
		558481 GNAO_DROME (1-354): 5.29e-165: 466: 87.01		Q9VB22_DROME (2-150): 8.32e-13: 73.1: 23.18
+	Hs
		444753 GNAI3_HUMAN (1-354): 2.32e-169: 477: 69.86		PCP2_HUMAN (408-510): 7.94e-10: 59.1: 29.25
+	Dm
		592742 GNAI_DROME (1-354): 9.15e-159: 450: 61.80		Q9NFR7_DROME (2-150): 4.29e-13: 74.3: 23.18
+	Dm
		592743 GNAI_DROME (1-354): 9.15e-159: 450: 61.80		Q9VB22_DROME (2-150): 8.32e-13: 73.1: 23.18