Protein: PAR1
Proteinase-activated receptor 1 (PAR-1) (Coagulation factor II receptor) (Thrombin receptor)

Gene: PAR1, F2R
Organism: Homo sapiens
Interactions: 30
UniProt ID: P25116

Gene Ontology (top 5):
GO:0001965 - G-protein alpha-subunit binding
GO:0002248 - connective tissue replacement involved in inflammatory response wound healing
GO:0003105 - negative regulation of glomerular filtration
GO:0004930 - G protein-coupled receptor activity
GO:0005102 - signaling receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

669387

GNA13
Guanine nucleotide-binding protein subunit alpha-13

2

19

Small-scale

0.776

High

669396

ARRD3
Arrestin domain-containing protein 3

2

16

Small-scale

0.768

High

669380

GRPR
Gastrin-releasing peptide receptor

1

17

High-throughput

0.691

High

343136

CXL14
C-X-C motif chemokine 14

1

1

Small-scale

0.647

High

128594

PAR3
Proteinase-activated receptor 3

1

17

Small-scale

0.618

High

418598

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

19

Small-scale

0.618

High

669382

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

20

Small-scale

0.618

High

669383

GNA12
Guanine nucleotide-binding protein subunit alpha-12

1

19

Small-scale

0.618

High

669391

MK14
Mitogen-activated protein kinase 14

1

4

Small-scale

0.618

High

669384

CAV1
Caveolin-1

2

6

Small-scale

0.611

High

669395

PDC6I
Programmed cell death 6-interacting protein

3

2

Small-scale

0.606

High

669402

EPCR
Endothelial protein C receptor

2

0

Small-scale

0.585

High

669385

SNX1
Sorting nexin-1

1

1

Small-scale

0.561

High

669400

AT132
Polyamine-transporting ATPase 13A2

1

20

Small-scale

0.541

High

366094

THRB
Prothrombin

1

5

Small-scale

0.501

High

669393

ARMC6
Armadillo repeat-containing protein 6

1

4

High-throughput

0.489

High

669403

CRYL1
Lambda-crystallin homolog

1

2

High-throughput

0.489

High

669381

SYUA
Alpha-synuclein

1

3

High-throughput

0.481

High

158775

AP3D1
AP-3 complex subunit delta-1

1

3

Small-scale

0.479

High

669386

FLOT2
Flotillin-2

1

4

Small-scale

0.479

High

669388

TMED2
Transmembrane emp24 domain-containing protein 2

1

7

Small-scale

0.479

High

669390

ZYX
Zyxin

1

1

Small-scale

0.479

High

669389

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

0

Small-scale

0.458

High

669397

CHM4A
Charged multivesicular body protein 4a

1

0

Small-scale

0.458

High

669401

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

1

0

Small-scale

0.458

High

255983

S19A2
Thiamine transporter 1

1

7

High-throughput

0.445

High

669392

GASP1
G-protein coupled receptor-associated sorting protein 1

1

8

Small-scale

0.437

High

669399

CHRD
Chordin

1

0

High-throughput

0.251

Low

669394

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.249

Low

669398

S17A9
Voltage-gated purine nucleotide uniporter SLC17A9

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025