Protein: AGTR1
Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) (AT1 receptor)

Gene: AGTR1
Organism: Homo sapiens
Interactions: 97
UniProt ID: P30556

Gene Ontology (top 5):
GO:0001558 - regulation of cell growth
GO:0001596 - angiotensin type I receptor activity
GO:0001822 - kidney development
GO:0002018 - renin-angiotensin regulation of aldosterone production
GO:0002034 - maintenance of blood vessel diameter homeostasis by renin-angiotensin

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

720645

ARRB2
Beta-arrestin-2

4

12

Small-scale

0.898

High

720648

APJ
Apelin receptor

2

18

Small-scale

0.789

High

720650

PF2R
Prostaglandin F2-alpha receptor

1

19

Small-scale

0.756

High

720652

ARRB1
Beta-arrestin-1

2

12

Small-scale

0.754

High

719498

BKRB2
B2 bradykinin receptor

1

17

High-throughput

0.698

High

720661

GNA12
Guanine nucleotide-binding protein subunit alpha-12

1

12

High-throughput

0.698

High

255991

S19A2
Thiamine transporter 1

3

6

High-throughput

0.667

High

661229

AT2B4
Plasma membrane calcium-transporting ATPase 4

3

20

High-throughput

0.667

High

720651

SC6A8
Sodium- and chloride-dependent creatine transporter 1

3

4

High-throughput

0.667

High

720657

AT12A
Potassium-transporting ATPase alpha chain 2

3

20

High-throughput

0.667

High

720662

CAV1
Caveolin-1

3

4

High-throughput

0.667

High

720669

AT2B3
Plasma membrane calcium-transporting ATPase 3

3

20

High-throughput

0.667

High

400357

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

5

Small-scale

0.665

High

703452

MK01
Mitogen-activated protein kinase 1

1

2

Small-scale

0.665

High

720666

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

High-throughput

0.618

High

669106

ARBK1
Beta-adrenergic receptor kinase 1

1

13

Small-scale

0.618

High

720646

GRK5
G protein-coupled receptor kinase 5

1

13

Small-scale

0.618

High

720649

5HT2B
5-hydroxytryptamine receptor 2B

1

19

Small-scale

0.618

High

720653

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

14

Small-scale

0.618

High

349385

TSN15
Tetraspanin-15

2

20

High-throughput

0.611

High

602196

TMM11
Transmembrane protein 11, mitochondrial

2

4

High-throughput

0.611

High

631083

RAB5A
Ras-related protein Rab-5A

2

4

Small-scale

0.595

High

720693

ACE2
Angiotensin-converting enzyme 2

2

2

Small-scale

0.595

High

720709

FBW1B
F-box/WD repeat-containing protein 11

1

0

High-throughput

0.584

High

420769

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

1

High-throughput

0.582

High

720676

CERS6
Ceramide synthase 6

1

19

High-throughput

0.582

High

720659

RACK1
Small ribosomal subunit protein RACK1

1

2

Small-scale

0.553

High

212549

GPAA1
GPI-anchor transamidase component GPAA1

1

1

High-throughput

0.541

High

269481

PLCH2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2

1

1

High-throughput

0.541

High

328865

RTN3
Reticulon-3

1

10

High-throughput

0.541

High

535911

CD37
Leukocyte antigen CD37

1

20

High-throughput

0.541

High

592807

CBR1
Carbonyl reductase [NADPH] 1

1

3

High-throughput

0.541

High

658637

JAK1
Tyrosine-protein kinase JAK1

1

20

High-throughput

0.541

High

690762

1433T
14-3-3 protein theta

1

7

High-throughput

0.541

High

720660

BASP1
Brain acid soluble protein 1

1

1

High-throughput

0.541

High

720665

SERC3
Serine incorporator 3

1

4

High-throughput

0.541

High

720672

UBR4
E3 ubiquitin-protein ligase UBR4

1

1

High-throughput

0.541

High

720686

AP2M1
AP-2 complex subunit mu

1

4

High-throughput

0.541

High

720688

FNBP1
Formin-binding protein 1

1

2

High-throughput

0.541

High

720691

GDIR3
Rho GDP-dissociation inhibitor 3

1

2

High-throughput

0.541

High

720695

RBNS5
Rabenosyn-5

1

7

High-throughput

0.541

High

720700

AT131
Endoplasmic reticulum transmembrane helix translocase

1

20

High-throughput

0.541

High

720702

T161A
Transmembrane protein 161A

1

6

High-throughput

0.541

High

720706

ABI3
ABI gene family member 3

1

6

High-throughput

0.541

High

720707

SAE1
SUMO-activating enzyme subunit 1

1

1

High-throughput

0.541

High

720708

ADDG
Gamma-adducin

1

2

High-throughput

0.541

High

720711

LZTS1
Leucine zipper putative tumor suppressor 1

1

3

High-throughput

0.541

High

720712

NPTN
Neuroplastin

1

5

High-throughput

0.541

High

298312

DNJC8
DnaJ homolog subfamily C member 8

1

2

High-throughput

0.532

High

720656

OAZ1
Ornithine decarboxylase antizyme 1

1

1

High-throughput

0.532

High

720655

MOT1
Monocarboxylate transporter 1

1

0

High-throughput

0.518

High

720668

L2GL1
Lethal(2) giant larvae protein homolog 1

1

0

High-throughput

0.518

High

720678

PPR3F
Protein phosphatase 1 regulatory subunit 3F

1

0

High-throughput

0.518

High

720680

CCD25
Coiled-coil domain-containing protein 25

1

0

High-throughput

0.518

High

720687

TMM80
Transmembrane protein 80

1

0

High-throughput

0.518

High

720675

ATRAP
Type-1 angiotensin II receptor-associated protein

1

2

Small-scale

0.501

High

176759

NACAD
NAC-alpha domain-containing protein 1

1

2

High-throughput

0.494

High

295459

PSD10
26S proteasome non-ATPase regulatory subunit 10

1

6

High-throughput

0.494

High

429122

7B2
Neuroendocrine protein 7B2

1

1

High-throughput

0.494

High

602743

AATC
Aspartate aminotransferase, cytoplasmic

1

1

High-throughput

0.494

High

643421

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

1

High-throughput

0.494

High

720670

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

1

1

High-throughput

0.494

High

720674

K0930
Uncharacterized protein KIAA0930

1

1

High-throughput

0.494

High

720694

BRD8
Bromodomain-containing protein 8

1

1

High-throughput

0.494

High

720696

GHITM
Growth hormone-inducible transmembrane protein

1

2

High-throughput

0.494

High

720699

HHATL
Protein-cysteine N-palmitoyltransferase HHAT-like protein

1

2

High-throughput

0.494

High

720703

FA13B
Protein FAM13B

1

5

High-throughput

0.494

High

720705

JKAMP
JNK1/MAPK8-associated membrane protein

1

1

High-throughput

0.494

High

720710

NDRG2
Protein NDRG2

1

4

High-throughput

0.494

High

253307

JAK2
Tyrosine-protein kinase JAK2

1

18

Small-scale

0.479

High

369536

ANGT
Angiotensinogen

1

11

Small-scale

0.479

High

720647

PGH2
Prostaglandin G/H synthase 2

1

1

Small-scale

0.479

High

720654

RAB7A
Ras-related protein Rab-7a

1

5

Small-scale

0.479

High

720689

CLCC1
Chloride channel CLIC-like protein 1

1

2

High-throughput

0.479

High

720698

PIGU
GPI-anchor transamidase component PIGU

1

2

High-throughput

0.479

High

720663

VAC14
Protein VAC14 homolog

1

9

High-throughput

0.470

High

618993

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

1

Small-scale

0.445

High

720667

CNCG
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

1

1

High-throughput

0.439

High

630700

RAB4A
Ras-related protein Rab-4A

1

3

Small-scale

0.437

High

720671

AG10A
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

1

8

High-throughput

0.437

High

720681

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

5

High-throughput

0.437

High

720684

SETD7
Histone-lysine N-methyltransferase SETD7

1

3

High-throughput

0.437

High

720701

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

1

4

High-throughput

0.437

High

221238

DCX
Neuronal migration protein doublecortin

2

0

High-throughput

0.328

High

252511

SEP15
Selenoprotein F

1

0

High-throughput

0.282

High

720664

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

1

0

High-throughput

0.282

High

720677

LCNL1
Lipocalin-like 1 protein

1

0

High-throughput

0.282

High

720679

HDGR2
Hepatoma-derived growth factor-related protein 2

1

0

High-throughput

0.282

High

720682

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

0

High-throughput

0.282

High

720683

PNMA1
Paraneoplastic antigen Ma1

1

0

High-throughput

0.282

High

720685

BAALC
Brain and acute leukemia cytoplasmic protein

1

0

High-throughput

0.282

High

720690

NUP88
Nuclear pore complex protein Nup88

1

0

High-throughput

0.282

High

720692

DBND2
Dysbindin domain-containing protein 2

1

0

High-throughput

0.282

High

720697

CUED2
CUE domain-containing protein 2

1

0

High-throughput

0.282

High

720704

SPG21
Maspardin

1

0

High-throughput

0.282

High

720658

RB11A
Ras-related protein Rab-11A

1

0

Small-scale

0.249

Low

720673

THOC7
THO complex subunit 7

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025