HitPredict

Interactor 1: CBX5 (P45973)
Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
Gene: CBX5

Interactor 2: ZBTB2 (Q8N680)
Zinc finger and BTB domain-containing protein 2
Gene: ZBTB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33301849
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 514
+	Hs
		67044 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		ZN726_HUMAN (62-513): 7.9e-173: 502: 14.72
+	Hs
		1097380 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		ZN534_HUMAN (87-513): 8.62e-153: 453: 13.30
+	Hs
		853234 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		ZN543_HUMAN (80-447): 8.46e-135: 404: 14.32
+	Hs
		853283 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		ZN568_HUMAN (185-513): 5.93e-106: 331: 16.27
+	Hs
		1097324 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		ZN568_HUMAN (185-513): 5.93e-106: 331: 16.27
+	Hs
		61162 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		A2VDJ6_HUMAN (217-498): 7.75e-89: 283: 18.96
+	Hs
		599990 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		ZNF16_HUMAN (288-513): 3.34e-69: 236: 14.98
+	Hs
		585028 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		ZN250_HUMAN (345-513): 2.82e-68: 230: 18.82
+	Hs
		1097422 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		ZN283_HUMAN (77-304): 1.17e-57: 205: 10.47
+	Hs
		853287 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		Z585B_HUMAN (354-513): 4.86e-47: 176: 16.15
+	Hs
		638597 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		ZNF10_HUMAN (262-498): 7.9e-48: 176: 15.06
+	Hs
		70999 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		ZN724_HUMAN (68-223): 2.01e-35: 141: 5.59
+	Hs
		853290 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		ZN569_HUMAN (73-189): 4.07e-23: 105: 8.20
+	Hs
		776911 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		ZNF93_HUMAN (413-514): 1.28e-24: 109: 14.71
+	Hs
		853375 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		ZN479_HUMAN (427-513): 2.5e-16: 83.7: 14.94
+	Hs
		853380 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		ZN578_HUMAN (245-458): 2.33e-12: 71.2: 28.70
+	Hs
		853307 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		Z585A_HUMAN (252-466): 2.45e-09: 62: 27.06
+	Hs
		853291 CBX5_HUMAN (1-191): 1.25e-68: 209: 100.00		ZN678_HUMAN (354-466): 7.36e-09: 60.1: 32.76
+	Hs
		1097386 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		ZN571_HUMAN (245-466): 4.56e-10: 63.9: 27.23
+	Hs
		1051147 CBX3_HUMAN (1-181): 3.08e-62: 192: 60.22		ZNF91_HUMAN (245-480): 1.42e-09: 62.8: 23.97