HitPredict

Interactor 1: IMA5 (P52294)
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]
Gene: KPNA1

Interactor 2: MTA3 (Q9BTC8)
Metastasis-associated protein MTA3
Gene: MTA3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 538 Hs			1 594
+	Hs
		168665 IMA6_HUMAN (1-538): 1.39e-152: 449: 79.59		MTA3_HUMAN (1-594): 0: 724: 100.00
+	Hs
		91456 IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00		E7EQY4_HUMAN (1-510): 0: 630: 99.41
+	Hs
		853588 IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00		MTA1_HUMAN (1-586): 0: 627: 69.14
+	Hs
		134890 IMA3_HUMAN (1-538): 7e-156: 456: 45.84		MTA1_HUMAN (1-586): 0: 627: 69.14
+	Hs
		131430 IMA4_HUMAN (3-538): 1.73e-150: 443: 45.91		MTA1_HUMAN (1-586): 0: 627: 69.14
+	Hs
		295971 IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00		MTA2_HUMAN (1-584): 0: 611: 64.40
+	Hs
		134816 IMA3_HUMAN (1-538): 7e-156: 456: 45.84		MTA2_HUMAN (1-584): 0: 611: 64.40
+	Hs
		295970 IMA1_HUMAN (3-538): 1.64e-149: 441: 44.36		MTA2_HUMAN (1-584): 0: 611: 64.40
+	Hs
		134987 IMA3_HUMAN (1-538): 7e-156: 456: 45.84		NCOR2_HUMAN (53-566): 2.01e-95: 322: 14.10
+	Hs
		131502 IMA4_HUMAN (3-538): 1.73e-150: 443: 45.91		Q9BRL8_HUMAN (462-586): 2.65e-43: 157: 46.88
+	Hs
		261446 IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00		NCOR1_HUMAN (267-577): 2.53e-09: 62.7: 11.54