HitPredict

Interactor 1: JAK1 (P52332)
Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)
Gene: JAK1

Interactor 2: PHAG1 (Q3U1F9)
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane phosphoprotein Cbp)
Gene: Pag1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26512138
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0035556 - intracellular signal transduction
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1153 Mm			1 429
+	Mm
		411925 LCK_MOUSE (795-1151): 3.59e-95: 315: 27.93		PHAG1_MOUSE (1-429): 0: 785: 100.00
+	Mm
		763390 FYN_MOUSE (842-1150): 6.77e-95: 315: 28.07		PHAG1_MOUSE (1-429): 0: 785: 100.00
+	Mm
		639443 LYN_MOUSE (816-1151): 7.19e-90: 300: 28.49		PHAG1_MOUSE (1-429): 0: 785: 100.00
+	Hs
		337571 ABL1_HUMAN (846-1153): 1.11e-94: 329: 30.42		PHAG1_HUMAN (1-429): 0: 705: 78.21
+	Hs
		523175 SRC_HUMAN (806-1150): 1.86e-97: 322: 26.59		PHAG1_HUMAN (1-429): 0: 705: 78.21
+	Hs
		412375 FYN_HUMAN (842-1150): 6.7e-95: 315: 28.07		PHAG1_HUMAN (1-429): 0: 705: 78.21
+	Hs
		411873 LCK_HUMAN (795-1151): 6.41e-95: 314: 28.77		PHAG1_HUMAN (1-429): 0: 705: 78.21
+	Hs
		789135 FRK_HUMAN (866-1150): 1.16e-93: 311: 36.24		PHAG1_HUMAN (1-429): 0: 705: 78.21
+	Hs
		434038 LYN_HUMAN (816-1151): 2.98e-90: 301: 28.19		PHAG1_HUMAN (1-429): 0: 705: 78.21
+	Mm
		796501 ZAP70_MOUSE (613-840): 3.25e-16: 85.5: 28.33		PHAG1_MOUSE (1-429): 0: 785: 100.00
+	Hs
		796485 ZAP70_HUMAN (613-840): 3.91e-17: 88.6: 28.75		PHAG1_HUMAN (1-429): 0: 705: 78.21