Interactor 1: RAGP1 (P46060)
Ran GTPase-activating protein 1 (RanGAP1)
Gene: RANGAP1

Interactor 2: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.993

The method score is based on:

Property Details
Experiments 18538659, 23395904, 16820290, 20501649, 16194093, 20719936, 21098080, 26496610, 28514442, 17353931, 28695742, 12924945, 29773808, 31575873, 32780723, 18691969, 33961781, 25412743, 37247759, 14578449 and 10 others

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Identification Methods enzymatic study, affinity chromatography technology, pull down, x-ray crystallography, two hybrid, molecular sieving, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RanGAP1_C~UQ_con
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0005654 - nucleoplasm
and 6 others

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Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 587
Hs

1 158
+ Hs
+ Mm
+ Rn
+ Sc
+ At
+ Ce
+ Zm

Service provided by Combinatics, Japan

Last updated: 11Aug2025