HitPredict

Interactor 1: HNRPF (P52597)
Heterogeneous nuclear ribonucleoprotein F (hnRNP F) (Nucleolin-like protein mcs94-1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein F, N-terminally processed]
Gene: HNRNPF

Interactor 2: HNRPD (Q14103)
Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1)
Gene: HNRNPD

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.775

Property	Details
Experiments	26318153, 22365833
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~zf-RNPHF
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006396 - RNA processing and 1 others more... GO:1990904 - ribonucleoprotein complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 415 Hs			1 355
+	Hs
		516511 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00
+	Hs
		161948 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63
+	Hs
		516663 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89
+	Hs
		516424 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		ROA3_HUMAN (64-265): 2.66e-50: 174: 37.02
+	Hs
		516495 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		PABP4_HUMAN (88-272): 4.65e-43: 159: 18.52
+	Hs
		516339 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93
+	Hs
		161970 HNRH1_HUMAN (1-413): 9.99e-69: 226: 74.82		HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63
+	Hs
		516358 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40
+	Hs
		609772 HNRPF_HUMAN (1-415): 1.26e-75: 242: 100.00		ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40
+	Hs
		609726 HNRH1_HUMAN (1-413): 9.99e-69: 226: 74.82		ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40
+	Hs
		453107 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Hs
		516689 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		PABP3_HUMAN (172-267): 5.97e-16: 80.9: 16.50
+	Hs
		453231 HNRPF_HUMAN (1-415): 1.26e-75: 242: 100.00		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Mm
		665745 PABP1_MOUSE (1-410): 5.26e-80: 260: 13.66		TIA1_MOUSE (176-270): 8.88e-14: 73.6: 18.75
+	Hs
		516471 PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66		TIAR_HUMAN (174-269): 2.98e-13: 72.1: 16.50
+	Hs
		201658 HNRPF_HUMAN (1-415): 1.26e-75: 242: 100.00		MSI1H_HUMAN (21-180): 2.38e-16: 81: 28.13
+	Mm
		857399 HNRPF_MOUSE (1-415): 2.75e-77: 247: 98.07		TIA1_MOUSE (176-270): 8.88e-14: 73.6: 18.75
+	Hs
		453174 HNRH1_HUMAN (1-413): 9.99e-69: 226: 74.82		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Mm
		193432 HNRH1_MOUSE (1-413): 9.27e-69: 226: 74.82		TIA1_MOUSE (176-270): 8.88e-14: 73.6: 18.75