HitPredict

Interactor 1: PPP5 (P53041)
Serine/threonine-protein phosphatase 5 (PP5) (EC 3.1.3.16) (Protein phosphatase T) (PP-T) (PPT)
Gene: PPP5C

Interactor 2: LRRC1 (Q9BTT6)
Leucine-rich repeat-containing protein 1 (LANO adapter protein) (LAP and no PDZ protein)
Gene: LRRC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28330616
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 499 Hs			1 524
+	Hs
		858616 PPP5_HUMAN (1-499): 0: 575: 100.00		FLII_HUMAN (5-207): 3.17e-34: 139: 28.02
+	Hs
		232821 PPP5_HUMAN (1-499): 0: 575: 100.00		PHLP1_HUMAN (312-524): 1.54e-18: 91.8: 17.70
+	Hs
		737994 PP1G_HUMAN (196-488): 1.79e-154: 444: 36.88		ERBIN_HUMAN (176-523): 1.94e-52: 194: 23.71
+	Hs
		906094 PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79		ERBIN_HUMAN (176-523): 1.94e-52: 194: 23.71
+	Hs
		737799 PP1G_HUMAN (196-488): 1.79e-154: 444: 36.88		SCRIB_HUMAN (186-522): 7.38e-50: 186: 19.24
+	Hs
		906454 PP1B_HUMAN (203-490): 1.32e-154: 444: 36.09		SCRIB_HUMAN (186-522): 7.38e-50: 186: 19.24
+	Hs
		905890 PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79		SCRIB_HUMAN (186-522): 7.38e-50: 186: 19.24
+	Dm
		1364726 Q9VH81_DROME (4-494): 8.41e-179: 513: 59.60		SUR8_DROME (309-521): 4.64e-23: 104: 13.64
+	Mm
		930640 PP2AA_MOUSE (190-481): 7.01e-167: 475: 40.88		ERBIN_MOUSE (269-523): 3.84e-34: 139: 19.84
+	Hs
		737779 PP1G_HUMAN (196-488): 1.79e-154: 444: 36.88		FLII_HUMAN (5-207): 3.17e-34: 139: 28.02
+	Hs
		906437 PP1B_HUMAN (203-490): 1.32e-154: 444: 36.09		FLII_HUMAN (5-207): 3.17e-34: 139: 28.02
+	Hs
		905863 PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79		FLII_HUMAN (5-207): 3.17e-34: 139: 28.02
+	Dm
		524646 PP12_DROME (209-479): 6.64e-158: 452: 38.97		SUR8_DROME (309-521): 4.64e-23: 104: 13.64
+	Hs
		738129 PP1G_HUMAN (196-488): 1.79e-154: 444: 36.88		SHOC2_HUMAN (284-514): 6.8e-23: 104: 20.69
+	Hs
		906638 PP1B_HUMAN (203-490): 1.32e-154: 444: 36.09		SHOC2_HUMAN (284-514): 6.8e-23: 104: 20.69
+	Dm
		524622 PP12_DROME (209-479): 6.64e-158: 452: 38.97		SCRIB_DROME (370-524): 6.62e-15: 80.3: 10.90
+	Mm
		906292 PP1A_MOUSE (200-479): 2.47e-154: 444: 38.79		LRRC1_MOUSE (370-524): 2.28e-09: 61.8: 12.26
+	Hs
		738009 PP1G_HUMAN (196-488): 1.79e-154: 444: 36.88		LRRC1_HUMAN (370-524): 2.72e-09: 61.4: 11.61
+	Hs
		906581 PP1B_HUMAN (203-490): 1.32e-154: 444: 36.09		LRRC1_HUMAN (370-524): 2.72e-09: 61.4: 11.61
+	Hs
		906110 PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79		LRRC1_HUMAN (370-524): 2.72e-09: 61.4: 11.61