Protein: DDB1
DNA damage-binding protein 1 (D-DDB1) (Damage-specific DNA-binding protein 1) (Protein piccolo)

Gene: DDB1, pic
Organism: Drosophila melanogaster
Interactions: 74
UniProt ID: Q9XYZ5

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006281 - DNA repair
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1173998

L2DTL
Protein lethal(2)denticleless

2

14

High-throughput

0.737

High

1470140

Q9VC96
BRWD3

2

16

High-throughput

0.737

High

911806

POLO
Serine/threonine-protein kinase polo

1

8

High-throughput

0.698

High

1304427

Q8IP73
DET1- and DDB1-associated protein 1

2

1

High-throughput

0.675

High

746414

GPRK2
G protein-coupled receptor kinase 2

1

7

Small-scale

0.618

High

1203001

Q5BI50
Cullin-4A

1

18

Small-scale

0.618

High

1303771

AKT1
RAC serine/threonine-protein kinase

1

2

High-throughput

0.618

High

1475490

CRBN
Protein cereblon

1

1

Small-scale

0.618

High

1481778

Q9VMI1
F-box and WD repeat domain containing 5

1

1

Small-scale

0.618

High

1484700

Q9VR61
non-specific serine/threonine protein kinase

1

4

High-throughput

0.618

High

847952

SNRPA
U1 small nuclear ribonucleoprotein A

1

4

High-throughput

0.575

High

1467341

WARTS
Serine/threonine-protein kinase Warts

1

4

Small-scale

0.553

High

1473844

Q9VFF0
Mitochondrial-processing peptidase subunit beta

2

1

High-throughput

0.542

High

929167

DPOD1
DNA polymerase delta catalytic subunit

1

3

High-throughput

0.541

High

1479749

WDR12
Ribosome biogenesis protein WDR12 homolog

1

14

High-throughput

0.514

High

1489511

Q9W108
FI01540p

1

2

High-throughput

0.514

High

69014

MBD56
Methyl-CpG-binding domain protein 5/6 homolog sba

1

1

High-throughput

0.479

High

541252

KRAF1
Raf homolog serine/threonine-protein kinase Raf

1

2

High-throughput

0.479

High

1378614

FOXO
Forkhead box protein O

1

1

High-throughput

0.479

High

1474610

DCA12
DDB1- and CUL4-associated factor 12 homolog

1

2

Small-scale

0.479

High

1488666

Q9VYB1
Kinetochore protein NDC80

1

3

Small-scale

0.479

High

1489762

DCAF1
Protein mahjong

1

3

Small-scale

0.479

High

120432

M9PD17
Gigas, isoform B

1

0

Small-scale

0.458

High

654930

MA205
205 kDa microtubule-associated protein

1

2

High-throughput

0.445

High

887835

MCM2
DNA replication licensing factor Mcm2

1

1

High-throughput

0.445

High

1050959

SSRP1
FACT complex subunit Ssrp1

1

6

High-throughput

0.445

High

1177517

Q29QQ9
Ribosomal RNA-processing protein 42

1

1

High-throughput

0.445

High

1196601

Q4V5H1
Peptidyl-prolyl cis-trans isomerase

1

1

High-throughput

0.445

High

1266584

NCBP1
Nuclear cap-binding protein subunit 1

1

4

High-throughput

0.445

High

1306381

SPT16
FACT complex subunit spt16

1

1

High-throughput

0.445

High

1466543

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

8

High-throughput

0.445

High

1468821

Q9VB04
Protein CASC3

1

1

High-throughput

0.445

High

1475408

Q9VGZ2
FI06805p

1

2

High-throughput

0.445

High

1479010

Q9VK19
FI07225p

1

2

High-throughput

0.445

High

1481206

Q9VLS7
LD21067p

1

1

High-throughput

0.445

High

1487133

SMN
Survival motor neuron protein

1

1

High-throughput

0.445

High

1487623

Q9VW53
FI01414p

1

3

High-throughput

0.445

High

1488190

RUXG
Probable small nuclear ribonucleoprotein G

1

7

High-throughput

0.445

High

1488879

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

1

High-throughput

0.445

High

1489631

Q9W1M9
Exosome complex component RRP4

1

1

High-throughput

0.445

High

56919

A1ZAK3
Protein DEK

1

0

High-throughput

0.426

High

925883

SET
Protein SET

1

0

High-throughput

0.426

High

1305066

EXOS3
Exosome complex component RRP40

1

0

High-throughput

0.426

High

1440240

NASP
Nuclear autoantigenic sperm protein homolog

1

0

High-throughput

0.426

High

1470124

Q9VC93
Exosome complex exonuclease RRP44

1

0

High-throughput

0.426

High

1477867

RAGP1
Ran GTPase-activating protein

1

0

High-throughput

0.426

High

1485546

DBR1
Lariat debranching enzyme

1

0

High-throughput

0.426

High

1488353

SYRC
Probable arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

1488646

RRP12
RRP12-like protein

1

0

High-throughput

0.426

High

1490376

SYQ
Probable glutamine--tRNA ligase

1

0

High-throughput

0.426

High

1019533

AP2A
AP-2 complex subunit alpha

1

2

High-throughput

0.407

High

1264328

Q7K0L8
FLICE-associated huge protein, isoform A

1

1

High-throughput

0.407

High

1345094

WDR55
WD repeat-containing protein 55 homolog

1

10

High-throughput

0.407

High

1465948

RU2A
Probable U2 small nuclear ribonucleoprotein A'

1

10

High-throughput

0.407

High

1480005

Q9VKW8
U6 snRNA-associated Sm-like protein LSm4

1

6

High-throughput

0.407

High

1488827

Q9VYT3
FI23714p1

1

1

High-throughput

0.407

High

1490377

Q9Y134
RNA helicase

1

6

High-throughput

0.407

High

1019411

SMO
Protein smoothened

1

0

Small-scale

0.249

Low

1263618

Q7JZC9
Nnf1a

1

0

Small-scale

0.249

Low

1484035

GOLP3
Golgi phosphoprotein 3 homolog sauron

1

0

High-throughput

0.249

Low

53208

A1Z7K8
AaRS-interacting multifunctional protein 1

1

0

High-throughput

0.232

Low

1264958

Q7K1Q7
Ribosome assembly factor mrt4

1

0

High-throughput

0.232

Low

1466676

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.232

Low

1475025

IPO9
Importin-9

1

0

High-throughput

0.232

Low

1476752

Q9VHT5
Large ribosomal subunit protein uL1m

1

0

High-throughput

0.232

Low

1481409

Q9VM14
dihydrolipoyllysine-residue acetyltransferase

1

0

High-throughput

0.232

Low

1483333

RM10
Large ribosomal subunit protein uL10m

1

0

High-throughput

0.232

Low

1483366

Q9VPM0
GH06023p

1

0

High-throughput

0.232

Low

1485882

QTRT2
Queuine tRNA-ribosyltransferase accessory subunit 2

1

0

High-throughput

0.232

Low

1486764

RM39
Large ribosomal subunit protein mL39

1

0

High-throughput

0.232

Low

1488997

THUM1
THUMP domain-containing protein 1 homolog

1

0

High-throughput

0.232

Low

1489179

SAHH2
Adenosylhomocysteinase-like 1

1

0

High-throughput

0.232

Low

1490065

Q9W4J4
GM14292p

1

0

High-throughput

0.232

Low

1490375

Q9Y0Y5
Coatomer subunit epsilon

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025