Interactor 1: DAM1 (P53267)
DASH complex subunit DAM1 (DUO1 and MPS1-interacting protein 1) (Kinetochore assembly protein DAM1) (Outer kinetochore protein DAM1)
Gene: DAM1

Interactor 2: DAD1 (Q12248)
DASH complex subunit DAD1 (DUO1 and DAM1-interacting protein 1) (Outer kinetochore protein DAD1)
Gene: DAD1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.90 0.929

The method score is based on:

Property Details
Experiments 11283351, 11553702, 11756468, 12925767, 34313341, 12408861, 15640796, 32946748, 37968396, 20730753, 23267104
Identification Methods two hybrid pooling approach, coimmunoprecipitation, tandem affinity purification, two hybrid, affinity chromatography technology, biochemical, miniaturized immunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains DASH_Dad1~DASH_Dam1
Common GO terms GO:0005737 - cytoplasm
GO:0008608 - attachment of spindle microtubules to kinetochore
GO:0031116 - positive regulation of microtubule polymerization
GO:0042729 - DASH complex
GO:0044732 - mitotic spindle pole body
and 5 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024