Interactor 1: PLEC (Q15149)
Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)
Gene: PLEC

Interactor 2: PLEC (Q15149)
Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)
Gene: PLEC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.873

The method score is based on:

Property Details
Experiments 37071682, 25253489, 39358380, 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~CH, Plectin~Plectin, SH3_10~Spectrin_3, Spectrin_2~Spectrin_2, Spectrin_2~Spectrin_3, Spectrin_3~Spectrin_3
Common GO terms GO:0000902 - cell morphogenesis
GO:0002102 - podosome
GO:0002162 - dystroglycan binding
GO:0002522 - leukocyte migration involved in immune response
GO:0003334 - keratinocyte development
and 51 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 4684
Hs

1 4684
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Rn
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025