HitPredict

Interactor 1: DAPK1 (P53355)
Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)
Gene: DAPK1

Interactor 2: TWF1 (Q12792)
Twinfilin-1 (Protein A6) (Protein tyrosine kinase 9)
Gene: TWF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	25852190, 32707033
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0015629 - actin cytoskeleton
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1430 Hs			1 350
+	Hs
		862015 DAPK1_HUMAN (1-1430): 0: 1999: 100.00		DEST_HUMAN (4-138): 2.63e-40: 141: 18.59
+	Hs
		862133 DAPK1_HUMAN (1-1430): 0: 1999: 100.00		COF2_HUMAN (4-138): 2.83e-38: 136: 17.53
+	At
		1105925 CDPKB_ARATH (3-446): 6.06e-127: 405: 26.56		ADF3_ARATH (3-139): 1.74e-46: 156: 22.14
+	Hs
		225101 KCC1D_HUMAN (2-325): 9.17e-120: 381: 35.39		GMFG_HUMAN (178-312): 5.03e-41: 142: 22.86
+	Hs
		200150 DAPK3_HUMAN (1-376): 1.82e-120: 385: 60.00		COF2_HUMAN (4-138): 2.83e-38: 136: 17.53