HitPredict

Interactor 1: FOSB (P53539)
Protein FosB (FosB proto-oncogene, AP-1 transcription factor subunit) (G0/G1 switch regulatory protein 3) (Transcription factor AP-1 subunit FosB)
Gene: FOSB

Interactor 2: STK40 (Q8N2I9)
Serine/threonine-protein kinase 40 (EC 2.7.11.1) (SINK-homologous serine/threonine-protein kinase) (Sugen kinase 495) (SgK495)
Gene: STK40

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 338 Hs			1 435
+	Hs
		345337 FOS_HUMAN (1-338): 8.95e-29: 116: 34.24		MARK3_HUMAN (3-433): 6.07e-121: 370: 19.55
+	Hs
		548318 FOSL2_HUMAN (1-338): 9.55e-33: 125: 38.61		STK40_HUMAN (1-435): 7.15e-121: 360: 100.00
+	Hs
		548254 FOSL1_HUMAN (54-338): 8.08e-31: 119: 39.04		STK40_HUMAN (1-435): 7.15e-121: 360: 100.00
+	Hs
		345487 FOS_HUMAN (1-338): 8.95e-29: 116: 34.24		STK40_HUMAN (1-435): 7.15e-121: 360: 100.00
+	Hs
		681869 NF2L2_HUMAN (7-218): 1.08e-25: 109: 22.97		AKT1_HUMAN (6-401): 2.8e-119: 358: 21.14
+	Hs
		402242 JUN_HUMAN (9-229): 4.9e-24: 102: 16.60		STK40_HUMAN (1-435): 7.15e-121: 360: 100.00
+	Hs
		566775 JUNB_HUMAN (97-224): 3.12e-22: 97.5: 28.24		STK40_HUMAN (1-435): 7.15e-121: 360: 100.00
+	Hs
		862631 FOSB_HUMAN (1-338): 5.83e-47: 163: 100.00		TRIB1_HUMAN (155-325): 4.48e-30: 121: 39.31
+	Hs
		548326 FOSL2_HUMAN (1-338): 9.55e-33: 125: 38.61		TRIB1_HUMAN (155-325): 4.48e-30: 121: 39.31
+	Hs
		548261 FOSL1_HUMAN (54-338): 8.08e-31: 119: 39.04		TRIB1_HUMAN (155-325): 4.48e-30: 121: 39.31
+	Hs
		345527 FOS_HUMAN (1-338): 8.95e-29: 116: 34.24		TRIB1_HUMAN (155-325): 4.48e-30: 121: 39.31
+	Hs
		345378 FOS_HUMAN (1-338): 8.95e-29: 116: 34.24		AAPK2_HUMAN (162-379): 1.47e-24: 107: 31.36
+	Hs
		871409 Q6FG41_HUMAN (1-338): 8.95e-29: 116: 34.24		AAPK2_HUMAN (162-379): 1.47e-24: 107: 31.36
+	Hs
		566786 JUNB_HUMAN (97-224): 3.12e-22: 97.5: 28.24		TRIB1_HUMAN (155-325): 4.48e-30: 121: 39.31
+	Hs
		579283 ATF4_HUMAN (17-220): 5.64e-22: 96.8: 15.42		TRIB3_HUMAN (161-325): 4.49e-25: 107: 38.10