Interactor 1: PRS10 (P53549)
26S proteasome subunit RPT4 (26S protease subunit SUG2) (Proteasomal cap subunit)
Gene: RPT4

Interactor 2: PRS8 (Q01939)
26S proteasome regulatory subunit 8 homolog (Protein CIM3) (Protein SUG1) (Tat-binding protein TBY1)
Gene: RPT6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 8955118, 19061648, 16554755, 18467557, 36621624, 23900548, 37968396
Identification Methods two hybrid, molecular sieving, coimmunoprecipitation, affinity chromatography technology, protein complementation assay, dihydrofolate reductase reconstruction, tandem affinity purification
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~Prot_ATP_ID_OB, AAA_lid_3~AAA_lid_3, Prot_ATP_ID_OB~Prot_ATP_ID_OB
Common GO terms GO:0000502 - proteasome complex
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0006289 - nucleotide-excision repair
GO:0008540 - proteasome regulatory particle, base subcomplex
and 8 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 437
Sc

1 405
+ At
+ Dm
+ Hs
+ At
+ Dm
+ Hs
+ Dm
+ Hs
+ Rn
+ At
+ At
+ Dm
+ Dm
+ Hs
+ Hs
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+ Dm
+ Rn
+ Sc
+ Sc

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Last updated: 15 Jul 2024