Interactor 1: DCP2 (P53550)
m7GpppN-mRNA hydrolase (EC 3.6.1.62) (Protein PSU1) (mRNA-decapping enzyme subunit 2)
Gene: DCP2

Interactor 2: DCP1 (Q12517)
mRNA-decapping enzyme subunit 1
Gene: DCP1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.981

The method score is based on:

Property Details
Experiments 16341225, 10688190, 10508173, 11805826, 16554755, 16429126, 30275269, 18719252, 26184073, 11741542, 18280238, 37968396
Identification Methods two hybrid array, two hybrid, coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, enzymatic study, biochemical, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains DCP1~DCP2, DCP1~NUDIX
Common GO terms GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000932 - P-body
GO:0003729 - mRNA binding
GO:0005634 - nucleus
and 5 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 970
Sc

1 231
+ Kl

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024