HitPredict

Interactor 1: ARPC2 (P53731)
Actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC)
Gene: ARC35

Interactor 2: LAS17 (Q12446)
Proline-rich protein LAS17
Gene: LAS17

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.690

Property	Details
Experiments	18467557, 37968396, 29386393, 21035341
Identification Methods	protein complementation assay, affinity chromatography technology, pull down, dihydrofolate reductase reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030041 - actin filament polymerization GO:0030479 - actin cortical patch GO:0045010 - actin nucleation
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 342 Sc			1 633
+	Hs
		126881 ARPC2_HUMAN (1-338): 1.92e-125: 363: 33.53		WASL_HUMAN (3-154): 1.13e-42: 163: 28.29
+	Bt
		1109661 ARPC2_BOVIN (1-338): 3.27e-126: 365: 33.82		WASL_BOVIN (3-154): 5.52e-38: 149: 28.29
+	Mm
		936474 ARPC2_MOUSE (1-338): 3.16e-126: 365: 33.82		WASP_MOUSE (3-386): 3.86e-37: 147: 18.37
+	Hs
		168896 ARPC2_HUMAN (1-338): 1.92e-125: 363: 33.53		WASP_HUMAN (3-448): 2.5e-27: 117: 16.52
+	Sp
		145141 ARPC2_SCHPO (1-341): 1.03e-124: 362: 40.40		WSP1_SCHPO (4-416): 3.99e-22: 102: 22.03