Interactor 1: RPAB4 (P53803)
DNA-directed RNA polymerases I, II, and III subunit RPABC4 (RNA polymerases I, II, and III subunit ABC4) (ABC10-alpha) (DNA-directed RNA polymerase II subunit K) (RNA polymerase II 7.0 kDa subunit) (RPB7.0) (RPB10alpha)
Gene: POLR2K

Interactor 2: RPA2 (Q9H9Y6)
DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135)
Gene: POLR1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 35271311, 24981860
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_RNApol_7kD~RNA_pol_Rpb2_1, DNA_RNApol_7kD~RNA_pol_Rpb2_6
Common GO terms GO:0001054 - RNA polymerase I activity
GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0005736 - RNA polymerase I complex
GO:0005829 - cytosol
and 1 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 58
Hs

1 1135
+ Hs
+ Hs
+ Sc
+ Sp
+ Sc
+ Sc

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Last updated: 15 Jul 2024