HitPredict

Interactor 1: UBP10 (P53874)
Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Disrupter of telomere silencing protein 4) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10)
Gene: UBP10

Interactor 2: UTP4 (Q06679)
U3 small nucleolar RNA-associated protein 4 (U3 snoRNA-associated protein 4) (U three protein 4) (U3 protein 4 required for transcription) (t-UTP4)
Gene: UTP4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22902402
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UCH~WD40
Common GO terms	GO:0005730 - nucleolus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 792 Sc			1 776
+	Sc
		965045 UBP3_YEAST (16-734): 4.12e-79: 275: 15.39		UTP4_YEAST (1-776): 1.17e-150: 460: 100.00
+	Sc
		635621 UBP10_YEAST (1-770): 5.85e-168: 506: 100.00		PWP2_YEAST (244-720): 2.31e-37: 152: 6.64
+	Sc
		630881 UBP10_YEAST (1-770): 5.85e-168: 506: 100.00		NLE1_YEAST (516-647): 4.72e-13: 74.3: 12.03
+	Hs
		254110 UBP7_HUMAN (162-786): 4e-90: 308: 13.21		WDR1_HUMAN (50-310): 6.11e-26: 115: 12.17
+	Hs
		903231 UBP10_HUMAN (11-734): 1.63e-93: 312: 15.96		WDR5_HUMAN (522-737): 1.2e-20: 95.7: 8.41
+	Hs
		903417 UBP7_HUMAN (162-786): 4e-90: 308: 13.21		WDR5_HUMAN (522-737): 1.2e-20: 95.7: 8.41
+	Hs
		1016340 UBP36_HUMAN (250-785): 2.88e-78: 275: 18.85		TBL3_HUMAN (341-716): 1.33e-23: 108: 9.09
+	Hs
		1350125 UBP36_HUMAN (250-785): 2.88e-78: 275: 18.85		WDR3_HUMAN (275-595): 1.21e-20: 99.6: 17.13
+	Hs
		1282726 UBP36_HUMAN (250-785): 2.88e-78: 275: 18.85		UTP4_HUMAN (410-699): 2.84e-20: 98: 8.48
+	Hs
		903571 UBP36_HUMAN (250-785): 2.88e-78: 275: 18.85		WDR5_HUMAN (522-737): 1.2e-20: 95.7: 8.41
+	Hs
		1256133 UBP36_HUMAN (250-785): 2.88e-78: 275: 18.85		UTP15_HUMAN (42-424): 1.73e-13: 75.7: 16.32
+	Hs
		1288358 UBP36_HUMAN (250-785): 2.88e-78: 275: 18.85		SNR40_HUMAN (182-501): 2.76e-12: 71.1: 15.27
+	Hs
		1346960 UBP36_HUMAN (250-785): 2.88e-78: 275: 18.85		NLE1_HUMAN (557-661): 1.4e-11: 69.5: 10.28
+	Hs
		1288312 UBP42_HUMAN (261-776): 8.85e-76: 270: 17.66		SNR40_HUMAN (182-501): 2.76e-12: 71.1: 15.27
+	Hs
		1121184 UBP39_HUMAN (135-737): 8.42e-77: 260: 13.66		SNR40_HUMAN (182-501): 2.76e-12: 71.1: 15.27
+	Hs
		1318177 UBP44_HUMAN (454-732): 3.22e-15: 81.6: 24.68		TBL1R_HUMAN (5-172): 3.08e-31: 130: 13.41
+	Hs
		903505 UBP44_HUMAN (454-732): 3.22e-15: 81.6: 24.68		WDR5_HUMAN (522-737): 1.2e-20: 95.7: 8.41