HitPredict

Interactor 1: NOP15 (P53927)
Ribosome biogenesis protein 15 (Nucleolar protein 15)
Gene: NOP15

Interactor 2: NOP12 (Q08208)
Nucleolar protein 12
Gene: NOP12

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	17922018, 37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0019843 - rRNA binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 220 Sc			1 459
+	Hs
		789536 MK67I_HUMAN (60-220): 8.1e-40: 139: 28.73		RBM34_HUMAN (10-430): 4.45e-68: 225: 26.59
+	Hs
		516484 ELAV2_HUMAN (2-173): 1.13e-29: 114: 13.48		PABP1_HUMAN (175-459): 5.78e-60: 208: 14.58
+	Hs
		1020249 ELAV2_HUMAN (2-173): 1.13e-29: 114: 13.48		PABP4_HUMAN (175-459): 6.56e-58: 203: 13.54
+	Hs
		516339 PABP1_HUMAN (82-207): 1.24e-25: 105: 15.87		PABP1_HUMAN (175-459): 5.78e-60: 208: 14.58
+	Hs
		516495 PABP1_HUMAN (82-207): 1.24e-25: 105: 15.87		PABP4_HUMAN (175-459): 6.56e-58: 203: 13.54
+	Sc
		865735 NOP15_YEAST (1-220): 1.29e-46: 155: 100.00		NOP13_YEAST (27-400): 8.6e-41: 152: 17.73
+	Hs
		474019 ELAV2_HUMAN (2-173): 1.13e-29: 114: 13.48		PAB4L_HUMAN (175-459): 2.59e-52: 182: 15.28
+	Hs
		1020306 ELAV2_HUMAN (2-173): 1.13e-29: 114: 13.48		PABP5_HUMAN (9-359): 5.36e-46: 165: 12.30
+	Hs
		1119141 PAP1L_HUMAN (82-207): 1.06e-25: 105: 16.67		PABP5_HUMAN (9-359): 5.36e-46: 165: 12.30
+	Hs
		198898 RFOX2_HUMAN (19-183): 1.37e-35: 131: 19.88		ELAV1_HUMAN (154-360): 1.32e-32: 128: 13.85
+	Hs
		198880 RFOX2_HUMAN (19-183): 1.37e-35: 131: 19.88		ELAV2_HUMAN (37-360): 5.79e-32: 126: 11.49
+	Hs
		703388 CSTF2_HUMAN (91-193): 1.45e-32: 125: 22.22		ELAV1_HUMAN (154-360): 1.32e-32: 128: 13.85
+	Hs
		1020265 ELAV2_HUMAN (2-173): 1.13e-29: 114: 13.48		ELAV1_HUMAN (154-360): 1.32e-32: 128: 13.85
+	Xl
		1265032 ELAV2_XENLA (78-207): 4.49e-28: 110: 18.32		ELAV2_XENLA (50-360): 5.91e-33: 130: 13.39
+	Mm
		665745 PABP1_MOUSE (82-207): 1.29e-25: 105: 15.87		TIA1_MOUSE (273-459): 8.21e-34: 132: 12.23
+	Hs
		198894 RFOX2_HUMAN (19-183): 1.37e-35: 131: 19.88		SF3B4_HUMAN (269-458): 2.8e-22: 100: 14.56
+	Hs
		516471 PABP1_HUMAN (82-207): 1.24e-25: 105: 15.87		TIAR_HUMAN (271-459): 7.39e-31: 124: 13.16
+	Hs
		703438 CSTFT_HUMAN (80-177): 1.99e-32: 125: 23.47		CSTF2_HUMAN (269-354): 1.5e-14: 77.7: 28.74