Interactor 1: HDA1 (P53973)
Histone deacetylase HDA1 (EC 3.5.1.98)
Gene: HDA1

Interactor 2: HDA1 (P53973)
Histone deacetylase HDA1 (EC 3.5.1.98)
Gene: HDA1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.931

The method score is based on:

Property Details
Experiments 27665728, 18719252, 19573535, 21179020, 11287668
Identification Methods pull down, x-ray crystallography, two hybrid, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Arb2~Arb2, Arb2~Hist_deacetyl, Hist_deacetyl~Hist_deacetyl
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003682 - chromatin binding
GO:0004407 - histone deacetylase activity
GO:0005737 - cytoplasm
and 3 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 706
Sc

1 706
+ Sp
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024