HitPredict

Interactor 1: CAZA2 (P47755)
F-actin-capping protein subunit alpha-2 (CapZ alpha-2)
Gene: CAPZA2

Interactor 2: COF2 (Q9Y281)
Cofilin-2 (Cofilin, muscle isoform)
Gene: CFL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0015629 - actin cytoskeleton GO:0051015 - actin filament binding GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 286 Hs			1 166
+	Hs
		659992 CAZA2_HUMAN (1-286): 2.45e-159: 446: 100.00		COF1_HUMAN (1-166): 3.76e-73: 218: 80.72
+	Hs
		866659 CAZA2_HUMAN (1-286): 2.45e-159: 446: 100.00		TWF1_HUMAN (3-156): 3.6e-33: 121: 21.66
+	Hs
		915070 CAZA1_HUMAN (1-286): 5.86e-156: 438: 86.71		TWF1_HUMAN (3-156): 3.6e-33: 121: 21.66
+	Hs
		866723 CAZA2_HUMAN (1-286): 2.45e-159: 446: 100.00		TWF2_HUMAN (3-151): 2.44e-29: 111: 18.42
+	Hs
		915113 CAZA1_HUMAN (1-286): 5.86e-156: 438: 86.71		TWF2_HUMAN (3-151): 2.44e-29: 111: 18.42