Interactor 1: ATX3 (P54252)
Ataxin-3 (EC 3.4.19.12) (Machado-Joseph disease protein 1) (Spinocerebellar ataxia type 3 protein)
Gene: ATXN3

Interactor 2: TERA (P55072)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: VCP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.767

The method score is based on:

Property Details
Experiments 25231079, 27851749, 28275011, 28180282, 12944474, 30455355, 14749733, 19843543, 16822850, 19175675, 22970133, 27762274, 29540532, 28939772, 18199748, 20414249, 23383273, 24100225, 16525503, 32814053
Identification Methods pull down, x-ray crystallography, affinity chromatography technology, two hybrid, proximity labelling technology, unspecified method, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, peptide array, competition binding and 3 others

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Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
and 4 others

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Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 361
Hs

1 806
+ Mm
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024