HitPredict

Interactor 1: ATX1 (P54253)
Ataxin-1 (Spinocerebellar ataxia type 1 protein)
Gene: ATXN1

Interactor 2: ATX2 (Q99700)
Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein)
Gene: ATXN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	16713569, 32814053
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, two hybrid pooling approach, validated two hybrid, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 815 Hs			1 1313
+	Hs
		868542 ATX1_HUMAN (1-815): 0: 1349: 100.00		OBSCN_HUMAN (105-1254): 3.4e-93: 335: 13.86
+	Hs
		868647 ATX1_HUMAN (1-815): 0: 1349: 100.00		ATX2L_HUMAN (521-1304): 2.92e-19: 96.4: 18.02
+	Hs
		868703 ATX1_HUMAN (1-815): 0: 1349: 100.00		MINT_HUMAN (431-1274): 9.87e-12: 72.1: 8.75
+	Hs
		868698 ATX1_HUMAN (1-815): 0: 1349: 100.00		CIC_HUMAN (3-783): 2.62e-10: 67.5: 10.47
+	Mm
		869051 ATX1_MOUSE (1-815): 0: 1271: 86.89		ATX2L_MOUSE (324-1030): 6.73e-12: 72.5: 9.17
+	Mm
		869164 ATX1_MOUSE (1-815): 0: 1271: 86.89		CIC_MOUSE (3-946): 4.88e-09: 63.2: 11.19
+	Hs
		473553 ATX1L_HUMAN (1-815): 3.55e-108: 348: 27.15		CIC_HUMAN (3-783): 2.62e-10: 67.5: 10.47