Protein: WDTC1
WD and tetratricopeptide repeats protein 1

Gene: WDTC1
Organism: Homo sapiens
Interactions: 168
UniProt ID: Q8N5D0

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001701 - in utero embryonic development
GO:0004857 - enzyme inhibitor activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1157814

DDB1
DNA damage-binding protein 1

9

20

Small-scale

0.972

High

610769

TCPA
T-complex protein 1 subunit alpha

4

20

High-throughput

0.892

High

821450

TCPZ
T-complex protein 1 subunit zeta

4

20

High-throughput

0.892

High

1007141

TCPB
T-complex protein 1 subunit beta

4

20

High-throughput

0.892

High

1327590

DDA1
DET1- and DDB1-associated protein 1

4

8

High-throughput

0.892

High

882030

TCPG
T-complex protein 1 subunit gamma

3

20

High-throughput

0.855

High

899477

TCPD
T-complex protein 1 subunit delta

3

20

High-throughput

0.855

High

1103634

PHLP
Phosducin-like protein

3

6

High-throughput

0.855

High

1327572

TCPW
T-complex protein 1 subunit zeta-2

3

20

High-throughput

0.855

High

1327587

TCPH
T-complex protein 1 subunit eta

3

20

High-throughput

0.855

High

876067

TCPE
T-complex protein 1 subunit epsilon

3

20

High-throughput

0.839

High

1327628

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

2

13

High-throughput

0.811

High

1132523

NAA30
N-alpha-acetyltransferase 30

2

5

High-throughput

0.776

High

1114938

CUL4A
Cullin-4A

11

20

Small-scale

0.755

High

1115298

CUL4B
Cullin-4B

5

20

Small-scale

0.720

High

822757

VHL
von Hippel-Lindau disease tumor suppressor

1

3

High-throughput

0.665

High

1327576

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.656

High

1162832

H2A2C
Histone H2A type 2-C

1

11

High-throughput

0.648

High

1012217

RT11
Small ribosomal subunit protein uS11m

4

10

High-throughput

0.630

High

1165234

RHG44
Rho GTPase-activating protein 44

2

6

High-throughput

0.628

High

1327601

EKI1
Ethanolamine kinase 1

2

2

High-throughput

0.628

High

156052

SOCS6
Suppressor of cytokine signaling 6

2

10

High-throughput

0.621

High

285365

EED
Polycomb protein EED

1

18

High-throughput

0.618

High

992855

RACK1
Small ribosomal subunit protein RACK1

1

20

High-throughput

0.618

High

1161939

H31T
Histone H3.1t

1

13

High-throughput

0.618

High

1163057

H2B2E
Histone H2B type 2-E

1

12

High-throughput

0.618

High

1202205

DCAF6
DDB1- and CUL4-associated factor 6

1

19

High-throughput

0.618

High

1227060

A16L1
Autophagy-related protein 16-1

1

19

High-throughput

0.618

High

1327566

WDTC1
WD and tetratricopeptide repeats protein 1

1

18

High-throughput

0.618

High

1327611

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

12

High-throughput

0.618

High

1327617

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

2

High-throughput

0.618

High

1327619

FBW1B
F-box/WD repeat-containing protein 11

1

19

High-throughput

0.618

High

166684

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

3

3

High-throughput

0.609

High

1327598

GHC1
Mitochondrial glutamate carrier 1

3

8

High-throughput

0.609

High

1257274

STXB4
Syntaxin-binding protein 4

3

5

High-throughput

0.604

High

1327615

SEPT3
Neuronal-specific septin-3

3

4

High-throughput

0.604

High

958670

CSN2
COP9 signalosome complex subunit 2

2

14

High-throughput

0.601

High

1094372

CSN1
COP9 signalosome complex subunit 1

2

11

High-throughput

0.601

High

1104612

IKZF1
DNA-binding protein Ikaros

2

9

High-throughput

0.601

High

1327579

BOD1
Biorientation of chromosomes in cell division protein 1

2

2

High-throughput

0.601

High

1327584

CSN8
COP9 signalosome complex subunit 8

2

3

High-throughput

0.601

High

1327624

NUDC
Nuclear migration protein nudC

2

18

High-throughput

0.584

High

899130

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.575

High

941809

ARL4C
ADP-ribosylation factor-like protein 4C

1

11

High-throughput

0.575

High

1327596

PDCL3
Phosducin-like protein 3

1

5

High-throughput

0.575

High

1327612

CSN7A
COP9 signalosome complex subunit 7a

2

7

High-throughput

0.571

High

1272485

CSN6
COP9 signalosome complex subunit 6

2

7

High-throughput

0.552

High

756569

GALNS
N-acetylgalactosamine-6-sulfatase

2

2

High-throughput

0.549

High

1108883

PNOC
Prepronociceptin [Cleaved into: Nocistatin; Nociceptin

2

1

High-throughput

0.549

High

209611

SERA
D-3-phosphoglycerate dehydrogenase

1

9

High-throughput

0.536

High

355087

APBA3
Amyloid-beta A4 precursor protein-binding family A member 3

1

3

High-throughput

0.536

High

848047

AL3B1
Aldehyde dehydrogenase family 3 member B1

1

9

High-throughput

0.536

High

1327580

TET5A
Terminal nucleotidyltransferase 5A

1

1

High-throughput

0.536

High

1327581

SPB11
Serpin B11

1

7

High-throughput

0.536

High

1327593

UCK2
Uridine-cytidine kinase 2

1

2

High-throughput

0.536

High

1327607

DECR2
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

1

2

High-throughput

0.536

High

1327621

CSN3
COP9 signalosome complex subunit 3

1

12

High-throughput

0.536

High

1258135

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

1

0

High-throughput

0.517

High

155121

SOCS2
Suppressor of cytokine signaling 2

1

11

High-throughput

0.515

High

1244170

TM10B
tRNA methyltransferase 10 homolog B

1

0

High-throughput

0.513

High

1327591

FUT8
Alpha-(1,6)-fucosyltransferase

1

0

High-throughput

0.513

High

1327613

CGBP1
CGG triplet repeat-binding protein 1

1

0

High-throughput

0.513

High

1327592

PG12A
Group XIIA secretory phospholipase A2

1

0

High-throughput

0.493

High

908640

PRELP
Prolargin

1

4

High-throughput

0.489

High

1030190

IL5RA
Interleukin-5 receptor subunit alpha

1

8

High-throughput

0.489

High

1327568

ZPLD1
Zona pellucida-like domain-containing protein 1

1

2

High-throughput

0.489

High

1327604

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

Small-scale

0.481

High

124811

AIP
AH receptor-interacting protein

1

19

High-throughput

0.479

High

144295

ACACB
Acetyl-CoA carboxylase 2

1

18

High-throughput

0.479

High

173068

XPO1
Exportin-1

1

20

High-throughput

0.479

High

182158

PFD6
Prefoldin subunit 6

1

7

High-throughput

0.479

High

183353

ZN185
Zinc finger protein 185

1

1

High-throughput

0.479

High

215328

TXNL1
Thioredoxin-like protein 1

1

17

High-throughput

0.479

High

242275

PRKN
E3 ubiquitin-protein ligase parkin

1

16

High-throughput

0.479

High

248736

PEPL
Periplakin

1

20

High-throughput

0.479

High

283506

TAD2A
Transcriptional adapter 2-alpha

1

16

High-throughput

0.479

High

294015

CD123
Translation initiation factor eIF2 assembly protein

1

3

High-throughput

0.479

High

328442

SCEL
Sciellin

1

1

High-throughput

0.479

High

346661

TTC4
Tetratricopeptide repeat protein 4

1

20

High-throughput

0.479

High

425824

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

1

16

High-throughput

0.479

High

425927

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

20

High-throughput

0.479

High

445025

S10A9
Protein S100-A9

1

3

High-throughput

0.479

High

447217

NPM
Nucleophosmin

1

6

High-throughput

0.479

High

468594

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.479

High

480849

LEG1
Galectin-1

1

9

High-throughput

0.479

High

547168

PYC
Pyruvate carboxylase, mitochondrial

1

18

High-throughput

0.479

High

587737

DESP
Desmoplakin

1

19

High-throughput

0.479

High

596232

H12
Histone H1.2

1

11

High-throughput

0.479

High

637631

FLNA
Filamin-A

1

12

High-throughput

0.479

High

772904

MYH9
Myosin-9

1

5

High-throughput

0.479

High

831061

CCNF
Cyclin-F

1

8

High-throughput

0.479

High

849375

RANG
Ran-specific GTPase-activating protein

1

3

High-throughput

0.479

High

859358

RL5
Large ribosomal subunit protein uL18

1

3

High-throughput

0.479

High

892266

5NTC
Cytosolic purine 5'-nucleotidase

1

1

High-throughput

0.479

High

916688

PPP5
Serine/threonine-protein phosphatase 5

1

7

High-throughput

0.479

High

943273

RBM11
Splicing regulator RBM11

1

11

High-throughput

0.479

High

963326

PFD3
Prefoldin subunit 3

1

9

High-throughput

0.479

High

965088

WDR5
WD repeat-containing protein 5

1

17

High-throughput

0.479

High

976414

RB11A
Ras-related protein Rab-11A

1

2

High-throughput

0.479

High

983885

RBX1
E3 ubiquitin-protein ligase RBX1

1

5

High-throughput

0.479

High

1038664

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

18

High-throughput

0.479

High

1094211

ACACA
Acetyl-CoA carboxylase 1

1

18

High-throughput

0.479

High

1113687

CUL3
Cullin-3

1

20

Small-scale

0.479

High

1121461

KEAP1
Kelch-like ECH-associated protein 1

1

6

High-throughput

0.479

High

1131014

LPIN1
Phosphatidate phosphatase LPIN1

1

1

High-throughput

0.479

High

1135739

HAPR1
HUWE1-associated protein modifying stress responses 1

1

2

High-throughput

0.479

High

1158425

CDC37
Hsp90 co-chaperone Cdc37

1

6

High-throughput

0.479

High

1160000

SRSF7
Serine/arginine-rich splicing factor 7

1

16

High-throughput

0.479

High

1161023

FSCN1
Fascin

1

1

High-throughput

0.479

High

1191444

GRDN
Girdin

1

20

High-throughput

0.479

High

1213778

KPRP
Keratinocyte proline-rich protein

1

2

High-throughput

0.479

High

1257733

VP13C
Intermembrane lipid transfer protein VPS13C

1

3

High-throughput

0.479

High

1280336

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

13

High-throughput

0.479

High

1308555

NUDC3
NudC domain-containing protein 3

1

18

High-throughput

0.479

High

1312636

MSRB3
Methionine-R-sulfoxide reductase B3

1

1

High-throughput

0.479

High

1327567

KNL1
Outer kinetochore KNL1 complex subunit KNL1

1

2

High-throughput

0.479

High

1327570

PP4R1
Serine/threonine-protein phosphatase 4 regulatory subunit 1

1

7

High-throughput

0.479

High

1327571

NUDC2
NudC domain-containing protein 2

1

18

High-throughput

0.479

High

1327573

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

7

High-throughput

0.479

High

1327574

CSN5
COP9 signalosome complex subunit 5

1

13

High-throughput

0.479

High

1327575

GLMN
Glomulin

1

2

High-throughput

0.479

High

1327577

CHM4C
Charged multivesicular body protein 4c

1

5

High-throughput

0.479

High

1327582

PFD5
Prefoldin subunit 5

1

7

High-throughput

0.479

High

1327583

DNJC7
DnaJ homolog subfamily C member 7

1

20

High-throughput

0.479

High

1327597

UN45A
Protein unc-45 homolog A

1

20

High-throughput

0.479

High

1327599

CSN7B
COP9 signalosome complex subunit 7b

1

7

High-throughput

0.479

High

1327600

CYBP
Calcyclin-binding protein

1

2

High-throughput

0.479

High

1327602

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

20

High-throughput

0.479

High

1327605

PFD4
Prefoldin subunit 4

1

5

High-throughput

0.479

High

1327609

PIHD1
PIH1 domain-containing protein 1

1

3

High-throughput

0.479

High

1327610

WHRN
Whirlin

1

3

High-throughput

0.479

High

1327614

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

1327616

PFD2
Prefoldin subunit 2

1

5

High-throughput

0.479

High

1327618

XPO7
Exportin-7

1

20

High-throughput

0.479

High

1327622

SRRM2
Serine/arginine repetitive matrix protein 2

1

20

High-throughput

0.479

High

1327623

RUVB2
RuvB-like 2

1

5

High-throughput

0.479

High

176689

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.458

High

1327578

KBP
KIF-binding protein

1

0

High-throughput

0.458

High

1327585

METH
Methionine synthase

1

0

High-throughput

0.458

High

1327606

SIAS
N-acetylneuraminate-9-phosphate synthase

1

0

High-throughput

0.458

High

1327620

MED23
Mediator of RNA polymerase II transcription subunit 23

1

1

Small-scale

0.457

High

1155008

ADIPO
Adiponectin

1

11

High-throughput

0.445

High

1157374

EXT1
Exostosin-1

1

2

High-throughput

0.445

High

1327588

CSN4
COP9 signalosome complex subunit 4

1

3

High-throughput

0.445

High

1327627

COPG1
Coatomer subunit gamma-1

1

6

High-throughput

0.445

High

189705

STX7
Syntaxin-7

1

1

High-throughput

0.437

High

342252

BRD1
Bromodomain-containing protein 1

1

11

High-throughput

0.437

High

345197

ZMYM6
Zinc finger MYM-type protein 6

1

3

High-throughput

0.437

High

350612

TXD12
Thioredoxin domain-containing protein 12

1

5

High-throughput

0.437

High

717541

PDIA3
Protein disulfide-isomerase A3

1

10

High-throughput

0.437

High

1308395

ANKY2
Ankyrin repeat and MYND domain-containing protein 2

1

14

High-throughput

0.437

High

1327603

ZCC17
Zinc finger CCHC domain-containing protein 17

1

6

High-throughput

0.437

High

1327608

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

8

Small-scale

0.437

High

73835

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

1

10

High-throughput

0.407

High

1197829

S39AC
Zinc transporter ZIP12

1

4

High-throughput

0.407

High

1279057

RIC3
Protein RIC-3

1

1

High-throughput

0.407

High

1288629

GPAT4
Glycerol-3-phosphate acyltransferase 4

1

2

High-throughput

0.407

High

1327594

SEM4C
Semaphorin-4C

1

2

High-throughput

0.407

High

1251829

PPR21
Protein phosphatase 1 regulatory subunit 21

3

0

High-throughput

0.345

High

1327586

MIPEP
Mitochondrial intermediate peptidase

3

0

High-throughput

0.345

High

289793

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

High-throughput

0.279

Low

1327569

PXYP1
2-phosphoxylose phosphatase 1

1

0

High-throughput

0.279

Low

1327595

CHST5
Carbohydrate sulfotransferase 5

1

0

High-throughput

0.279

Low

1327626

COQ4
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial

1

0

High-throughput

0.279

Low

880805

NRAM1
Natural resistance-associated macrophage protein 1

1

0

High-throughput

0.232

Low

1327589

TR61B
tRNA

1

0

High-throughput

0.232

Low

1327625

S35A3
UDP-N-acetylglucosamine transporter

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025