HitPredict

Interactor 1: MLC2 (P54357)
Myosin-2 essential light chain (Myosin II essential light chain) (Non-muscle myosin essential light chain)
Gene: Mlc-c

Interactor 2: ASP (Q9VC45)
Protein abnormal spindle
Gene: ASP

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	16917818
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EF-hand_6~IQ, EF-hand_7~IQ
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Dm			1 1954
+	Dm
		906705 CALM_DROME (3-146): 1.12e-46: 149: 43.45		ASP_DROME (1-1954): 0: 1651: 100.00
+	Ce
		183769 CALM_CAEEL (3-146): 1.26e-46: 149: 42.76		O17666_CAEEL (614-1527): 2.3e-102: 360: 15.06
+	Hs
		484206 CALM3_HUMAN (3-146): 3.02e-47: 151: 43.45		MYO5C_HUMAN (1277-1926): 1.42e-28: 128: 13.71
+	Gg
		361265 MYL6_CHICK (1-147): 3.11e-55: 171: 54.31		MYH11_CHICK (984-1843): 6e-22: 106: 8.65
+	Hs
		70646 MYL6B_HUMAN (3-146): 1.59e-47: 154: 53.38		MYO9A_HUMAN (1177-1790): 6.1e-24: 113: 13.71
+	Sc
		420223 CALM_YEAST (2-146): 1.14e-45: 147: 37.42		MYO2_YEAST (1150-1729): 2.08e-22: 108: 11.21
+	Hs
		148350 MYL6B_HUMAN (3-146): 1.59e-47: 154: 53.38		CTRO_HUMAN (830-1605): 1.03e-18: 95.8: 10.12
+	Dm
		51921 CALM_DROME (3-146): 1.12e-46: 149: 43.45		A1Z6Z9_DROME (1341-1771): 3.65e-19: 97.3: 13.92
+	Hs
		148595 MYL6_HUMAN (1-147): 1.81e-45: 147: 53.64		CTRO_HUMAN (830-1605): 1.03e-18: 95.8: 10.12
+	Hs
		484218 CALM3_HUMAN (3-146): 3.02e-47: 151: 43.45		MYO5B_HUMAN (1125-1834): 1.81e-15: 85: 9.34
+	Hs
		483950 CALM1_HUMAN (3-146): 3.02e-47: 151: 43.45		ASPM_HUMAN (880-1557): 2.3e-13: 78.4: 13.01
+	Hs
		484022 CALM2_HUMAN (3-146): 3.02e-47: 151: 43.45		ASPM_HUMAN (880-1557): 2.3e-13: 78.4: 13.01
+	Hs
		484165 CALM3_HUMAN (3-146): 3.02e-47: 151: 43.45		ASPM_HUMAN (880-1557): 2.3e-13: 78.4: 13.01
+	Hs
		538665 MYL6B_HUMAN (3-146): 1.59e-47: 154: 53.38		MYO9B_HUMAN (1033-1175): 4.78e-11: 70.6: 23.29
+	Hs
		483925 CALM1_HUMAN (3-146): 3.02e-47: 151: 43.45		MYO9B_HUMAN (1033-1175): 4.78e-11: 70.6: 23.29
+	Hs
		483999 CALM2_HUMAN (3-146): 3.02e-47: 151: 43.45		MYO9B_HUMAN (1033-1175): 4.78e-11: 70.6: 23.29
+	Hs
		484117 CALM3_HUMAN (3-146): 3.02e-47: 151: 43.45		MYO9B_HUMAN (1033-1175): 4.78e-11: 70.6: 23.29
+	Hs
		214479 CALM1_HUMAN (3-146): 3.02e-47: 151: 43.45		MYO1B_HUMAN (949-1141): 6.18e-11: 69.9: 18.87
+	Hs
		214480 CALM3_HUMAN (3-146): 3.02e-47: 151: 43.45		MYO1B_HUMAN (949-1141): 6.18e-11: 69.9: 18.87
+	Hs
		484202 CALM3_HUMAN (3-146): 3.02e-47: 151: 43.45		MYO10_HUMAN (1045-1347): 4.78e-09: 64.1: 11.41