Interactor 1: AAPK2 (P54646)
5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)
Gene: PRKAA2

Interactor 2: TRIP6 (Q15654)
Thyroid receptor-interacting protein 6 (TR-interacting protein 6) (TRIP-6) (Opa-interacting protein 1) (OIP-1) (Zyxin-related protein 1) (ZRP-1)
Gene: TRIP6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.695

The method score is based on:

Property Details
Experiments 16624523, 25416956, 19616115
Identification Methods affinity chromatography technology, two hybrid, enzymatic study, anti tag coimmunoprecipitation, in-gel kinase assay, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type physical association, direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0046872 - metal ion binding
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 552
Hs

1 476
+ Hs
+ Hs

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Last updated: 15 Jul 2024