HitPredict

Interactor 1: RD23B (P54727)
UV excision repair protein RAD23 homolog B (HR23B) (hHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58)
Gene: RAD23B

Interactor 2: UBC12 (P61081)
NEDD8-conjugating enzyme Ubc12 (EC 2.3.2.34) (NEDD8 carrier protein) (Ubiquitin-conjugating enzyme E2 M)
Gene: UBE2M

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28581483
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UBA~UQ_con, UQ_con~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 409 Hs			1 183
+	Hs
		829086 UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72		UBE2A_HUMAN (26-172): 2.67e-69: 208: 28.19
+	Zm
		27869 A0A1D6JMS0_MAIZE (2-407): 1.23e-51: 183: 15.43		A0A1D6LNL8_MAIZE (1-181): 7.11e-70: 212: 64.84
+	Dm
		639410 Q9VWD9_DROME (1-353): 1.07e-44: 164: 11.08		UBCD1_DROME (30-173): 5.31e-75: 223: 32.88
+	Mm
		476737 UBC_MOUSE (1-118): 1.78e-32: 131: 21.67		UB2D3_MOUSE (30-173): 1.29e-73: 219: 31.51
+	Hs
		475249 UBB_HUMAN (1-79): 1.99e-32: 123: 30.38		UB2D4_HUMAN (30-173): 3.96e-76: 226: 32.19
+	Hs
		474984 UBB_HUMAN (1-79): 1.99e-32: 123: 30.38		UB2D2_HUMAN (30-173): 3.54e-75: 223: 32.19
+	At
		1091932 UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75		UBC28_ARATH (30-174): 5.45e-76: 225: 31.29
+	Hs
		1137415 Q5U5U6_HUMAN (1-79): 1.99e-32: 123: 30.38		UB2E3_HUMAN (5-173): 2.2e-72: 218: 26.90
+	Hs
		475124 UBB_HUMAN (1-79): 1.99e-32: 123: 30.38		UB2E3_HUMAN (5-173): 2.2e-72: 218: 26.90
+	At
		715116 UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75		UBC8_ARATH (30-174): 1.21e-75: 225: 32.65
+	Hs
		895774 RL40_HUMAN (1-91): 3.57e-33: 122: 28.57		UB2D3_HUMAN (30-173): 1.29e-73: 219: 31.51
+	At
		715132 UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75		UBC9_ARATH (30-174): 3.95e-75: 223: 31.29
+	At
		715147 UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75		UBC10_ARATH (30-174): 5.61e-75: 223: 31.97
+	At
		715157 UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75		UBC11_ARATH (30-174): 1.28e-74: 222: 34.01
+	Hs
		474958 UBB_HUMAN (1-79): 1.99e-32: 123: 30.38		UBE2A_HUMAN (26-172): 2.67e-69: 208: 28.19
+	At
		639385 UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75		UBC1_ARATH (26-173): 7.67e-70: 210: 28.00
+	At
		790155 UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75		UBC2_ARATH (26-173): 5.52e-70: 210: 28.00
+	Hs
		895773 RS27A_HUMAN (1-90): 2.4e-15: 75: 26.67		UB2D3_HUMAN (30-173): 1.29e-73: 219: 31.51
+	Hs
		70479 B2RDW1_HUMAN (1-90): 2.4e-15: 75: 26.67		UB2E3_HUMAN (5-173): 2.2e-72: 218: 26.90
+	Hs
		896017 RS27A_HUMAN (1-90): 2.4e-15: 75: 26.67		UBC12_HUMAN (1-183): 5.92e-69: 209: 100.00