HitPredict

Interactor 1: H33A (C0HL66)
Histone H3.3A (H3.A)
Gene: His3.3A

Interactor 2: TIP60 (Q960X4)
Histone acetyltransferase Tip60 (EC 2.3.1.48)
Gene: TIP60

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	19079254
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~MOZ_SAS
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Dm			1 541
+	Hs
		998640 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		KAT5_HUMAN (23-541): 0: 707: 58.38
+	Hs
		1161982 H31T_HUMAN (1-136): 2.59e-59: 181: 93.38		KAT5_HUMAN (23-541): 0: 707: 58.38
+	Hs
		1258902 H32_HUMAN (1-136): 5.34e-59: 180: 97.06		KAT5_HUMAN (23-541): 0: 707: 58.38
+	Hs
		998815 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		KAT8_HUMAN (128-533): 2.59e-156: 455: 39.30
+	Hs
		1017214 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		KAT8_HUMAN (128-533): 2.59e-156: 455: 39.30
+	Hs
		331990 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		KAT7_HUMAN (260-533): 5.37e-149: 442: 53.79
+	Dm
		145736 H3_DROME (1-136): 5.34e-59: 180: 97.06		MOF_DROME (239-537): 4.3e-147: 444: 48.17
+	Hs
		331992 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		KAT7_HUMAN (260-533): 5.37e-149: 442: 53.79
+	Hs
		998630 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		KAT6A_HUMAN (84-533): 2.23e-137: 440: 35.64
+	Hs
		1017075 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		KAT6A_HUMAN (84-533): 2.23e-137: 440: 35.64
+	Hs
		1161976 H31T_HUMAN (1-136): 2.59e-59: 181: 93.38		KAT6A_HUMAN (84-533): 2.23e-137: 440: 35.64
+	Hs
		1258898 H32_HUMAN (1-136): 5.34e-59: 180: 97.06		KAT6A_HUMAN (84-533): 2.23e-137: 440: 35.64
+	Hs
		1239459 H3C_HUMAN (1-136): 2e-56: 173: 95.59		KAT6A_HUMAN (84-533): 2.23e-137: 440: 35.64
+	Hs
		998608 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		KAT6B_HUMAN (203-533): 4.78e-133: 428: 42.86
+	Hs
		1161964 H31T_HUMAN (1-136): 2.59e-59: 181: 93.38		KAT6B_HUMAN (203-533): 4.78e-133: 428: 42.86
+	Dm
		381745 H3_DROME (1-136): 5.34e-59: 180: 97.06		Q9W1A9_DROME (75-533): 4.53e-130: 420: 34.24
+	Hs
		331976 CENPA_HUMAN (9-133): 2.43e-45: 146: 50.76		KAT7_HUMAN (260-533): 5.37e-149: 442: 53.79
+	Hs
		883643 CENPA_HUMAN (9-133): 2.43e-45: 146: 50.76		KAT6A_HUMAN (84-533): 2.23e-137: 440: 35.64
+	Sc
		757771 H3_YEAST (1-136): 3.63e-54: 168: 90.44		SAS3_YEAST (247-533): 1.75e-118: 370: 42.37
+	Sc
		963767 H3_YEAST (1-136): 3.63e-54: 168: 90.44		ESA1_YEAST (3-85): 1.22e-11: 68.7: 33.33