HitPredict

Interactor 1: EPHA4 (P54764)
Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)
Gene: EPHA4

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Hormone_recep~fn3
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 986 Hs			1 530
+	Hs
		600510 EPHA1_HUMAN (17-973): 0: 970: 43.87		COT2_HUMAN (77-502): 2.24e-102: 316: 23.90
+	Hs
		368836 IGF1R_HUMAN (394-884): 1.97e-137: 447: 29.47		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		377124 UFO_HUMAN (268-928): 5.13e-150: 469: 23.72		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		523091 SRC_HUMAN (601-871): 2.14e-64: 229: 45.42		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		368894 SRC_HUMAN (601-871): 2.14e-64: 229: 45.42		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		522762 SRC_HUMAN (601-871): 2.14e-64: 229: 45.42		RXRA_HUMAN (13-502): 1.6e-119: 361: 25.71
+	Hs
		377007 FYN_HUMAN (615-879): 2.51e-66: 234: 44.20		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377057 SRC_HUMAN (601-871): 2.14e-64: 229: 45.42		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		487890 SRC_HUMAN (601-871): 2.14e-64: 229: 45.42		RARA_HUMAN (52-505): 3.54e-105: 324: 23.74
+	Hs
		414427 SRC_HUMAN (601-871): 2.14e-64: 229: 45.42		PRGR_HUMAN (149-459): 2.26e-41: 161: 32.82
+	Hs
		442764 HCK_HUMAN (573-879): 1.08e-66: 235: 41.29		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487088 SRC_HUMAN (601-871): 2.14e-64: 229: 45.42		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59