HitPredict

Interactor 1: KCNJ3 (P48549)
G protein-activated inward rectifier potassium channel 1 (GIRK-1) (Inward rectifier K(+) channel Kir3.1) (Potassium channel, inwardly rectifying subfamily J member 3)
Gene: KCNJ3

Interactor 2: KCNJ3 (P48549)
G protein-activated inward rectifier potassium channel 1 (GIRK-1) (Inward rectifier K(+) channel Kir3.1) (Potassium channel, inwardly rectifying subfamily J member 3)
Gene: KCNJ3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 16809021
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IRK~IRK, IRK~IRK_C, IRK_C~IRK_C
Common GO terms GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005886 - plasma membrane
GO:0006813 - potassium ion transport
GO:0008076 - voltage-gated potassium channel complex
GO:0009897 - external side of plasma membrane
and 15 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 501
Hs

1 501
+ Mm
+ Hs
+ Bt
+ Gg
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 11Aug2025