Protein: KCNJ6
G protein-activated inward rectifier potassium channel 2 (GIRK-2) (BIR1) (Inward rectifier K(+) channel Kir3.2) (KATP-2) (Potassium channel, inwardly rectifying subfamily J member 6)

Gene: KCNJ6
Organism: Homo sapiens
Interactions: 79
UniProt ID: P48051

Gene Ontology (top 5):
GO:0005242 - inward rectifier potassium channel activity
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0006813 - potassium ion transport
GO:0008076 - voltage-gated potassium channel complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

870061

KCNJ9
G protein-activated inward rectifier potassium channel 3

2

15

Small-scale

0.754

High

870086

LPAR3
Lysophosphatidic acid receptor 3

2

3

High-throughput

0.606

High

870075

CA043
Protein C1orf43

2

0

High-throughput

0.602

High

164908

TR10C
Tumor necrosis factor receptor superfamily member 10C

2

0

High-throughput

0.580

High

270002

XYLK
Glycosaminoglycan xylosylkinase

2

0

High-throughput

0.580

High

539462

ITAM
Integrin alpha-M

2

0

High-throughput

0.580

High

719056

MIP
Lens fiber major intrinsic protein

2

0

High-throughput

0.580

High

719877

HMOX2
Heme oxygenase 2

2

0

High-throughput

0.580

High

870041

PMP22
Peripheral myelin protein 22

2

0

High-throughput

0.580

High

870043

SREC
Scavenger receptor class F member 1

2

0

High-throughput

0.580

High

870047

RTP2
Receptor-transporting protein 2

2

0

High-throughput

0.580

High

870048

TSPO2
Translocator protein 2

2

0

High-throughput

0.580

High

870050

VSTM1
V-set and transmembrane domain-containing protein 1

2

0

High-throughput

0.580

High

870052

ZDH24
Probable palmitoyltransferase ZDHHC24

2

0

High-throughput

0.580

High

870054

PCAT2
Lysophosphatidylcholine acyltransferase 2

2

0

High-throughput

0.580

High

870057

NRAC
Nutritionally-regulated adipose and cardiac enriched protein homolog

2

0

High-throughput

0.580

High

870070

SYT3
Synaptotagmin-3

2

0

High-throughput

0.580

High

870078

FXYD6
FXYD domain-containing ion transport regulator 6

2

0

High-throughput

0.580

High

870082

AIG1
Androgen-induced gene 1 protein

2

0

High-throughput

0.580

High

870084

NINJ2
Ninjurin-2

2

0

High-throughput

0.580

High

870088

PLLP
Plasmolipin

2

0

High-throughput

0.580

High

870090

YIPF1
Protein YIPF1

2

0

High-throughput

0.580

High

870037

KCNJ5
G protein-activated inward rectifier potassium channel 4

1

15

High-throughput

0.575

High

870072

LRRC1
Leucine-rich repeat-containing protein 1

2

3

High-throughput

0.574

High

295675

UPK1B
Uroplakin-1b

2

1

High-throughput

0.553

High

458326

ADRB2
Beta-2 adrenergic receptor

1

2

High-throughput

0.541

High

870060

GOGA5
Golgin subfamily A member 5

1

3

High-throughput

0.536

High

658866

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

0

High-throughput

0.518

High

870079

PICK1
PRKCA-binding protein

1

0

High-throughput

0.518

High

870042

DLG1
Disks large homolog 1

1

20

Small-scale

0.501

High

870085

GABR1
Gamma-aminobutyric acid type B receptor subunit 1

1

1

Small-scale

0.501

High

870077

THS7B
Thrombospondin type-1 domain-containing protein 7B

1

0

High-throughput

0.493

High

572423

DRD2
D(2) dopamine receptor

1

8

Small-scale

0.479

High

870068

MY15B
Unconventional myosin-XVB

1

2

High-throughput

0.470

High

188656

BIRC5
Baculoviral IAP repeat-containing protein 5

1

1

Small-scale

0.457

High

870040

XIAP
E3 ubiquitin-protein ligase XIAP

1

1

Small-scale

0.457

High

565512

RARG
Retinoic acid receptor gamma

2

0

High-throughput

0.328

High

870056

M21D2
Nucleotidyltransferase MB21D2

2

0

High-throughput

0.328

High

870069

F118B
Protein FAM118B

2

0

High-throughput

0.328

High

870081

UFSP2
Ufm1-specific protease 2

2

0

High-throughput

0.328

High

870083

HPF1
Histone PARylation factor 1

2

0

High-throughput

0.328

High

49635

T120B
Transmembrane protein 120B

2

0

High-throughput

0.316

High

58647

SRTM1
Serine-rich and transmembrane domain-containing protein 1

2

0

High-throughput

0.316

High

60561

TM218
Transmembrane protein 218

2

0

High-throughput

0.316

High

144412

SCD
Stearoyl-CoA desaturase

2

0

High-throughput

0.316

High

179841

BET1
BET1 homolog

2

0

High-throughput

0.316

High

254278

ICMT
Protein-S-isoprenylcysteine O-methyltransferase

2

0

High-throughput

0.316

High

329622

LERL1
Leptin receptor overlapping transcript-like 1

2

0

High-throughput

0.316

High

391729

STAT
Statherin

2

0

High-throughput

0.316

High

423750

APOD
Apolipoprotein D

2

0

High-throughput

0.316

High

712091

CO4A5

2

0

High-throughput

0.316

High

870038

LIPR1
Inactive pancreatic lipase-related protein 1

2

0

High-throughput

0.316

High

870039

EP3B
Epididymal secretory protein E3-beta

2

0

High-throughput

0.316

High

870045

ORML2
ORM1-like protein 2

2

0

High-throughput

0.316

High

870046

UNC50
Protein unc-50 homolog

2

0

High-throughput

0.316

High

870051

TM107
Transmembrane protein 107

2

0

High-throughput

0.316

High

870053

TMPPE
Transmembrane protein with metallophosphoesterase domain

2

0

High-throughput

0.316

High

870062

B2CL2
Bcl-2-like protein 2

2

0

High-throughput

0.316

High

870063

SCAM4
Secretory carrier-associated membrane protein 4

2

0

High-throughput

0.316

High

870064

TM203
Transmembrane protein 203

2

0

High-throughput

0.316

High

870065

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

2

0

High-throughput

0.316

High

870066

YIPF6
Protein YIPF6

2

0

High-throughput

0.316

High

870067

PX11C
Peroxisomal membrane protein 11C

2

0

High-throughput

0.316

High

870071

CNPY3
Protein canopy homolog 3

2

0

High-throughput

0.316

High

870073

TM208
Transmembrane protein 208

2

0

High-throughput

0.316

High

870074

FUND2
FUN14 domain-containing protein 2

2

0

High-throughput

0.316

High

870076

TM6S2
Transmembrane 6 superfamily member 2

2

0

High-throughput

0.316

High

870080

RPRM
Protein reprimo

2

0

High-throughput

0.316

High

870087

ERG28
Ergosterol biosynthetic protein 28 homolog

2

0

High-throughput

0.316

High

870089

FIS1
Mitochondrial fission 1 protein

2

0

High-throughput

0.316

High

870091

PEX16
Peroxisomal membrane protein PEX16

2

0

High-throughput

0.316

High

870092

UBIA1
UbiA prenyltransferase domain-containing protein 1

2

0

High-throughput

0.316

High

167581

GIPC1
PDZ domain-containing protein GIPC1

1

0

High-throughput

0.282

High

870049

MAP1S
Microtubule-associated protein 1S

1

0

High-throughput

0.282

High

870055

CXXC5
CXXC-type zinc finger protein 5

1

0

High-throughput

0.282

High

870058

ZBT38
Zinc finger and BTB domain-containing protein 38

1

0

High-throughput

0.282

High

870059

NEUA
N-acylneuraminate cytidylyltransferase

1

0

High-throughput

0.282

High

870044

HSDL1
Inactive hydroxysteroid dehydrogenase-like protein 1

1

0

High-throughput

0.279

Low

516255

DWORF
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025