HitPredict

Interactor 1: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Interactor 2: NEB1 (Q9ULJ8)
Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A)
Gene: PPP1R9A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~PDZ, PDZ~PDZ_5
Common GO terms	GO:0051015 - actin filament binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1824 Hs			1 1098
+	Hs
		876372 AFAD_HUMAN (1-1824): 0: 1279: 100.00		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		876371 AFAD_HUMAN (1-1824): 0: 1279: 100.00		PTN13_HUMAN (2-937): 2.68e-18: 93.5: 11.65
+	Hs
		876446 AFAD_HUMAN (1-1824): 0: 1279: 100.00		INADL_HUMAN (300-819): 1.83e-15: 84: 10.38
+	Hs
		1066861 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		NEB1_HUMAN (1-1098): 6.8e-118: 392: 100.00
+	Rn
		192523 MYO5B_RAT (102-939): 4.23e-117: 413: 14.69		NEB2_RAT (1-826): 2.53e-45: 178: 43.42
+	Hs
		1021567 KI13B_HUMAN (184-691): 5.1e-66: 250: 12.64		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		1021494 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Dm
		51933 A1Z6Z9_DROME (102-924): 1.68e-103: 370: 14.56		PATJ_DROME (213-593): 2.18e-17: 89.8: 15.66
+	Hs
		942384 KI13B_HUMAN (184-691): 5.1e-66: 250: 12.64		DLG4_HUMAN (376-1098): 5.91e-50: 191: 13.13
+	Mm
		93501 E9Q4K7_MOUSE (184-691): 6.04e-63: 240: 12.41		DLG4_MOUSE (376-1098): 3.11e-50: 192: 13.00
+	Hs
		231509 KIF1B_HUMAN (191-589): 6.21e-42: 171: 15.66		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Rn
		292061 KIF1B_RAT (314-589): 6.15e-42: 171: 18.09		DLG1_RAT (225-1097): 1.18e-66: 244: 13.46
+	Hs
		1066562 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		NEB2_HUMAN (1-826): 1.2e-42: 170: 43.65
+	Hs
		231496 KIF1B_HUMAN (191-589): 6.21e-42: 171: 15.66		DLG4_HUMAN (376-1098): 5.91e-50: 191: 13.13
+	Rn
		292059 KIF1B_RAT (314-589): 6.15e-42: 171: 18.09		DLG4_RAT (376-1098): 9.51e-50: 191: 13.13
+	Hs
		876511 KI13B_HUMAN (184-691): 5.1e-66: 250: 12.64		AFAD_HUMAN (419-593): 1.96e-23: 110: 30.11
+	Hs
		1020223 KI13B_HUMAN (184-691): 5.1e-66: 250: 12.64		PTN13_HUMAN (2-937): 2.68e-18: 93.5: 11.65
+	Hs
		876388 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		AFAD_HUMAN (419-593): 1.96e-23: 110: 30.11
+	Hs
		280044 KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67		MPDZ_HUMAN (157-813): 4.92e-13: 75.9: 9.50
+	Rn
		291491 KIF1B_RAT (314-589): 6.15e-42: 171: 18.09		MAGI2_RAT (268-654): 1.73e-09: 64.4: 11.62