HitPredict

Interactor 1: NR2C2 (P49116)
Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear receptor TAK1) (Orphan nuclear receptor TR4) (Testicular receptor 4)
Gene: NR2C2

Interactor 2: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30463901, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 596 Hs			1 183
+	Hs
		853194 NR2C2_HUMAN (1-596): 0: 527: 100.00		CBX5_HUMAN (11-182): 1.63e-55: 175: 59.89
+	Hs
		878965 NR2C2_HUMAN (1-596): 0: 527: 100.00		CBX1_HUMAN (36-180): 1.03e-53: 170: 71.33
+	Hs
		879627 NR2C2_HUMAN (1-596): 0: 527: 100.00		CDYL_HUMAN (16-165): 6.56e-34: 127: 25.16
+	Dm
		1172404 HR78_DROME (82-580): 1.38e-77: 259: 25.39		Q95SE0_DROME (29-175): 3.41e-52: 168: 56.95
+	Dm
		1172528 HR78_DROME (82-580): 1.38e-77: 259: 25.39		Q9W396_DROME (29-175): 4.57e-52: 168: 56.95
+	Hs
		522809 COT1_HUMAN (47-193): 9.06e-48: 174: 41.45		CBX5_HUMAN (11-182): 1.63e-55: 175: 59.89
+	Hs
		520530 RARA_HUMAN (66-191): 1.29e-27: 118: 44.53		CBX5_HUMAN (11-182): 1.63e-55: 175: 59.89
+	Hs
		522777 NR2F6_HUMAN (386-576): 3.61e-24: 107: 36.13		CBX1_HUMAN (36-180): 1.03e-53: 170: 71.33
+	Hs
		216368 RARA_HUMAN (66-191): 1.29e-27: 118: 44.53		SUV91_HUMAN (3-179): 4.75e-40: 141: 16.20
+	Hs
		216442 Q15156_HUMAN (92-191): 6.45e-26: 115: 50.98		SUV91_HUMAN (3-179): 4.75e-40: 141: 16.20