HitPredict

Interactor 1: FCGRN (P55899)
IgG receptor FcRn large subunit p51 (FcRn) (IgG Fc fragment receptor transporter alpha chain) (Neonatal Fc receptor)
Gene: FCGRT

Interactor 2: B2MG (P61769)
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]
Gene: B2M

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.899

Property	Details
Experiments	28514442, 31289263, 33961781, 10933786
Identification Methods	affinity chromatography technology, x-ray crystallography, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	C1-set~C1-set, C1-set~MHC_I
Common GO terms	GO:0005615 - extracellular space GO:0009897 - external side of plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 365 Hs			1 119
+	Hs
		382258 HLAA_HUMAN (1-360): 8.54e-151: 431: 27.27		HLAA_HUMAN (2-116): 6.86e-47: 155: 22.41
+	Hs
		382277 HLAA_HUMAN (1-360): 8.54e-151: 431: 27.27		HLAC_HUMAN (2-117): 4.98e-46: 153: 19.66
+	Hs
		382321 HLAA_HUMAN (1-360): 8.54e-151: 431: 27.27		HLAF_HUMAN (2-116): 3.24e-45: 151: 25.00
+	Hs
		382467 HLAA_HUMAN (1-360): 8.54e-151: 431: 27.27		Q860B5_HUMAN (2-117): 8.26e-46: 151: 22.22
+	Hs
		901892 Q95J06_HUMAN (1-360): 2.76e-156: 445: 27.54		B2MG_HUMAN (1-119): 1.69e-42: 137: 100.00
+	Hs
		354248 HLAA_HUMAN (1-360): 8.54e-151: 431: 27.27		HLAB_HUMAN (2-117): 7.05e-44: 148: 19.66
+	Hs
		382299 HLAA_HUMAN (1-360): 8.54e-151: 431: 27.27		HLAG_HUMAN (2-116): 6.98e-44: 147: 22.41
+	Hs
		69943 B1PKZ2_HUMAN (1-360): 1.59e-153: 438: 26.20		B2MG_HUMAN (1-119): 1.69e-42: 137: 100.00
+	Hs
		354804 HLAA_HUMAN (1-360): 8.54e-151: 431: 27.27		DQA1_HUMAN (20-119): 4.08e-43: 143: 27.72
+	Hs
		92644 HLAA_HUMAN (1-360): 8.54e-151: 431: 27.27		E9PMV2_HUMAN (20-115): 5.18e-43: 141: 30.93
+	Hs
		382286 HLAA_HUMAN (1-360): 8.54e-151: 431: 27.27		HLAE_HUMAN (3-117): 8.23e-41: 140: 22.03
+	Hs
		382302 HLAA_HUMAN (1-360): 8.54e-151: 431: 27.27		DPA1_HUMAN (19-118): 1.53e-41: 139: 34.65
+	Hs
		382387 HLAA_HUMAN (1-360): 8.54e-151: 431: 27.27		DRB3_HUMAN (25-115): 2.56e-41: 139: 33.70
+	Hs
		382442 HLAA_HUMAN (1-360): 8.54e-151: 431: 27.27		DRB5_HUMAN (24-115): 5.4e-41: 138: 33.33
+	Hs
		382376 HLAA_HUMAN (1-360): 8.54e-151: 431: 27.27		B2MG_HUMAN (1-119): 1.69e-42: 137: 100.00
+	Hs
		355008 HLAA_HUMAN (1-360): 8.54e-151: 431: 27.27		DQB1_HUMAN (13-115): 4.62e-40: 135: 29.81
+	Hs
		901878 Q5S3G3_HUMAN (1-360): 2.93e-150: 429: 27.81		B2MG_HUMAN (1-119): 1.69e-42: 137: 100.00
+	Hs
		901879 Q5SUL5_HUMAN (1-360): 1.55e-147: 422: 27.81		B2MG_HUMAN (1-119): 1.69e-42: 137: 100.00
+	Mm
		354231 HA12_MOUSE (1-360): 4.41e-143: 411: 26.93		B2MG_MOUSE (1-119): 1.64e-43: 140: 68.07
+	Rn
		421721 HA12_RAT (1-359): 5.78e-145: 416: 25.94		B2MG_RAT (1-119): 7.63e-41: 133: 69.75