Interactor 1: CTBP2 (P56545)
C-terminal-binding protein 2 (CtBP2)
Gene: CTBP2

Interactor 2: PROX1 (Q92786)
Prospero homeobox protein 1 (Homeobox prospero-like protein PROX1) (PROX-1)
Gene: PROX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.573

The method score is based on:

Property Details
Experiments 21988832
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0008285 - negative regulation of cell population proliferation
GO:0045892 - negative regulation of DNA-templated transcription
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 445
Hs

1 737
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024