HitPredict

Interactor 1: H2BFS (P57053)
Histone H2B type F-S (H2B-clustered histone 12 like) (H2B.S histone 1) (Histone H2B.s) (H2B/s)
Gene: H2BC12L

Interactor 2: H2AV (Q71UI9)
Histone H2A.V (H2A.F/Z) (H2A.Z variant histone 2)
Gene: H2AZ2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~Histone, Histone~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 128
+	Hs
		1129818 H2B2F_HUMAN (1-126): 1.57e-54: 168: 96.03		H2AV_HUMAN (1-128): 7.15e-60: 182: 100.00
+	Hs
		469948 H2B1O_HUMAN (1-126): 2.43e-54: 168: 96.03		H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43
+	Hs
		470046 H2B2F_HUMAN (1-126): 1.57e-54: 168: 96.03		H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43
+	Hs
		420793 H2B1J_HUMAN (1-126): 4.25e-54: 167: 97.62		H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43
+	Hs
		1151403 U3KQK0_HUMAN (1-126): 2.67e-55: 171: 96.83		H2A2A_HUMAN (5-125): 7.47e-54: 166: 63.12
+	Hs
		391992 U3KQK0_HUMAN (1-126): 2.67e-55: 171: 96.83		H2A1B_HUMAN (5-125): 1.25e-53: 166: 62.30
+	Hs
		617950 H2B1O_HUMAN (1-126): 2.43e-54: 168: 96.03		H2A2C_HUMAN (5-128): 2.15e-54: 168: 62.40
+	Hs
		617974 H2B1O_HUMAN (1-126): 2.43e-54: 168: 96.03		H2AJ_HUMAN (5-128): 1.33e-54: 168: 60.80
+	Hs
		1307102 H2B1M_HUMAN (1-126): 3.27e-54: 167: 94.44		H2A1J_HUMAN (5-125): 1.65e-54: 168: 62.30
+	Hs
		391552 H2B1O_HUMAN (1-126): 2.43e-54: 168: 96.03		H2A1B_HUMAN (5-125): 1.25e-53: 166: 62.30
+	Hs
		391736 H2B2F_HUMAN (1-126): 1.57e-54: 168: 96.03		H2A1B_HUMAN (5-125): 1.25e-53: 166: 62.30
+	Hs
		470271 H2B1O_HUMAN (1-126): 2.43e-54: 168: 96.03		H2A1_HUMAN (5-125): 1.18e-53: 166: 62.30
+	Hs
		470411 H2B2F_HUMAN (1-126): 1.57e-54: 168: 96.03		H2A1_HUMAN (5-125): 1.18e-53: 166: 62.30
+	Hs
		555295 H2B1O_HUMAN (1-126): 2.43e-54: 168: 96.03		H2AX_HUMAN (5-124): 1.36e-53: 166: 62.81
+	Hs
		555496 H2B2F_HUMAN (1-126): 1.57e-54: 168: 96.03		H2AX_HUMAN (5-124): 1.36e-53: 166: 62.81
+	Hs
		594822 H2B1O_HUMAN (1-126): 2.43e-54: 168: 96.03		H2A1D_HUMAN (5-125): 9.61e-54: 166: 63.12
+	Hs
		617952 H2B1O_HUMAN (1-126): 2.43e-54: 168: 96.03		H2A2A_HUMAN (5-125): 7.47e-54: 166: 63.12
+	Hs
		391503 H2B1J_HUMAN (1-126): 4.25e-54: 167: 97.62		H2A1B_HUMAN (5-125): 1.25e-53: 166: 62.30
+	Hs
		391868 H2B1M_HUMAN (1-126): 3.27e-54: 167: 94.44		H2A1B_HUMAN (5-125): 1.25e-53: 166: 62.30
+	Hs
		555619 H2B1M_HUMAN (1-126): 3.27e-54: 167: 94.44		H2AX_HUMAN (5-124): 1.36e-53: 166: 62.81