HitPredict

Interactor 1: H2BFS (P57053)
Histone H2B type F-S (H2B-clustered histone 12 like) (H2B.S histone 1) (Histone H2B.s) (H2B/s)
Gene: H2BC12L

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21182203
Identification Methods	cosedimentation through density gradient
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 530
+	Hs
		617964 H2B1O_HUMAN (1-126): 2.43e-54: 168: 96.03		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		420866 H2B1J_HUMAN (1-126): 4.25e-54: 167: 97.62		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		241599 H2B1K_HUMAN (1-126): 7.6e-54: 166: 98.41		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		886167 H2B1D_HUMAN (1-126): 1.97e-53: 165: 96.83		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369710 H2B2E_HUMAN (1-126): 3.9e-54: 167: 96.83		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369335 H2B1C_HUMAN (1-126): 7.2e-54: 166: 97.62		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369274 H2B1D_HUMAN (1-126): 1.97e-53: 165: 96.83		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370296 H2B1L_HUMAN (1-126): 1.71e-52: 163: 96.03		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		487935 H2B1C_HUMAN (1-126): 7.2e-54: 166: 97.62		RARA_HUMAN (52-505): 3.54e-105: 324: 23.74
+	Hs
		487304 H2B1C_HUMAN (1-126): 7.2e-54: 166: 97.62		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59