Protein: ASAP1
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP)

Gene: ASAP1
Organism: Homo sapiens
Interactions: 71
UniProt ID: Q9ULH1

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0002102 - podosome
GO:0005096 - GTPase activator activity
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

988022

GRB2
Growth factor receptor-bound protein 2

10

20

High-throughput

0.976

High

1384299

SH3K1
SH3 domain-containing kinase-binding protein 1

8

20

Small-scale

0.965

High

855799

CRK
Adapter molecule crk

6

20

Small-scale

0.937

High

1124751

SRC8
Src substrate cortactin

5

16

Small-scale

0.936

High

222224

NCK2
Cytoplasmic protein NCK2

4

20

High-throughput

0.892

High

1311223

RHG12
Rho GTPase-activating protein 12

4

13

High-throughput

0.875

High

1051077

FAK1
Focal adhesion kinase 1

4

20

Small-scale

0.867

High

557518

SRC
Proto-oncogene tyrosine-protein kinase Src

3

15

Small-scale

0.867

High

440782

FYN
Tyrosine-protein kinase Fyn

3

15

Small-scale

0.827

High

1352031

ASAP3
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3

2

14

High-throughput

0.811

High

668751

APC
Adenomatous polyposis coli protein

2

8

Small-scale

0.806

High

878581

PAXI
Paxillin

2

5

Small-scale

0.789

High

619131

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

2

High-throughput

0.770

High

473483

HCK
Tyrosine-protein kinase HCK

2

15

Small-scale

0.768

High

594133

NCK1
SH2/SH3 adapter protein NCK1

2

20

Small-scale

0.768

High

975314

ARF6
ADP-ribosylation factor 6

2

15

Small-scale

0.768

High

1461574

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

2

6

Small-scale

0.768

High

1461575

CD2AP
CD2-associated protein

2

20

Small-scale

0.743

High

273147

RFIP3
Rab11 family-interacting protein 3

1

11

Small-scale

0.724

High

1014980

ARF1
ADP-ribosylation factor 1

1

14

Small-scale

0.692

High

855953

CRKL
Crk-like protein

1

20

High-throughput

0.691

High

508820

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

8

Small-scale

0.665

High

220815

PPIP1
Proline-serine-threonine phosphatase-interacting protein 1

1

6

Small-scale

0.647

High

292881

GRAP2
GRB2-related adapter protein 2

1

20

Small-scale

0.647

High

840901

TEC
Tyrosine-protein kinase Tec

1

15

Small-scale

0.647

High

1091595

DLG1
Disks large homolog 1

1

9

Small-scale

0.647

High

1368310

STAM1
Signal transducing adapter molecule 1

1

11

Small-scale

0.647

High

1408400

SH3G2
Endophilin-A1

1

14

Small-scale

0.647

High

1163991

DDR2
Discoidin domain-containing receptor 2

1

20

High-throughput

0.646

High

362407

ABL1
Tyrosine-protein kinase ABL1

1

15

High-throughput

0.618

High

412795

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.618

High

541752

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.618

High

648730

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.618

High

953755

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

988817

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

1055110

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

20

High-throughput

0.618

High

1150898

CIP4
Cdc42-interacting protein 4

1

8

Small-scale

0.618

High

1182874

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

1

1

High-throughput

0.618

High

1256061

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.618

High

1292590

FCSD1
F-BAR and double SH3 domains protein 1

1

12

Small-scale

0.618

High

1359648

ARAP3
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

1

18

Small-scale

0.618

High

1371090

ARHG2
Rho guanine nucleotide exchange factor 2

1

11

Small-scale

0.618

High

1411686

RHG09
Rho GTPase-activating protein 9

1

11

High-throughput

0.618

High

1417660

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

1

10

Small-scale

0.618

High

1461203

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

1

6

Small-scale

0.618

High

184335

NPHP1
Nephrocystin-1

1

0

Small-scale

0.614

High

1461576

SNX9
Sorting nexin-9

1

0

Small-scale

0.614

High

1327263

FBXL6
F-box/LRR-repeat protein 6

1

1

High-throughput

0.553

High

274803

DNJB6
DnaJ homolog subfamily B member 6

1

1

High-throughput

0.541

High

1097961

CBLB
E3 ubiquitin-protein ligase CBL-B

1

10

Small-scale

0.534

High

651461

CBL
E3 ubiquitin-protein ligase CBL

1

10

Small-scale

0.515

High

1454196

NHSL3
NHS-like protein 3

1

9

High-throughput

0.489

High

583017

EZRI
Ezrin

1

7

High-throughput

0.479

High

699891

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

10

High-throughput

0.479

High

971276

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

1050834

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

2

High-throughput

0.479

High

1250835

RFIP1
Rab11 family-interacting protein 1

1

10

Small-scale

0.479

High

1350498

BICD2
Protein bicaudal D homolog 2

1

1

High-throughput

0.479

High

556413

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

949460

EIF3E
Eukaryotic translation initiation factor 3 subunit E

1

0

High-throughput

0.458

High

986807

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.458

High

1450287

EXOC1
Exocyst complex component 1

1

1

High-throughput

0.457

High

191419

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

4

High-throughput

0.445

High

786926

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

2

High-throughput

0.445

High

106840

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

373468

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.437

High

522010

H14
Histone H1.4

1

3

High-throughput

0.437

High

1254041

PEAK3
Protein PEAK3

1

2

Small-scale

0.437

High

1272893

RFIP2
Rab11 family-interacting protein 2

1

13

Small-scale

0.437

High

129825

CBX4
E3 SUMO-protein ligase CBX4

1

3

High-throughput

0.407

High

330367

VENTX
Homeobox protein VENTX

1

1

High-throughput

0.407

High


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Last updated: 11Aug2025