HitPredict

Interactor 1: UBS3A (P57075)
Ubiquitin-associated and SH3 domain-containing protein A (Cbl-interacting protein 4) (CLIP4) (Suppressor of T-cell receptor signaling 2) (STS-2) (T-cell ubiquitin ligand 1) (TULA-1)
Gene: UBASH3A

Interactor 2: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31659016
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 661 Hs			1 375
+	Hs
		891919 UBS3B_HUMAN (1-655): 0: 904: 43.07		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		929939 UBS3B_HUMAN (1-655): 0: 904: 43.07		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		891770 LASP1_HUMAN (163-337): 3.87e-36: 138: 17.11		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Mm
		915552 LASP1_MOUSE (163-337): 6.96e-38: 143: 16.32		ACTA_MOUSE (2-375): 0: 591: 94.12
+	Hs
		282322 NEBL_HUMAN (188-340): 7.6e-29: 124: 20.12		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		235496 VINEX_HUMAN (202-339): 5.67e-28: 121: 22.86		ACTS_HUMAN (2-375): 0: 592: 93.58
+	Hs
		596202 NEBU_HUMAN (187-337): 3.33e-22: 104: 18.41		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		892005 SRBS1_HUMAN (145-339): 1.51e-20: 99.1: 21.46		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		891671 GRB2_HUMAN (245-341): 1.31e-22: 98.4: 25.25		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		924453 GRB2_HUMAN (245-341): 1.31e-22: 98.4: 25.25		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		596210 NEBU_HUMAN (187-337): 3.33e-22: 104: 18.41		ACTH_HUMAN (2-375): 0: 589: 93.58
+	Hs
		932362 SRBS1_HUMAN (145-339): 1.51e-20: 99.1: 21.46		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		924456 GRB2_HUMAN (245-341): 1.31e-22: 98.4: 25.25		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		924454 GRB2_HUMAN (245-341): 1.31e-22: 98.4: 25.25		ACTH_HUMAN (2-375): 0: 589: 93.58
+	Dm
		501505 LASP1_DROME (274-339): 1.44e-16: 85.6: 34.85		ACT1_DROME (2-375): 0: 598: 98.13
+	Dm
		361146 LASP1_DROME (274-339): 1.44e-16: 85.6: 34.85		ACT2_DROME (2-375): 0: 596: 97.59
+	Dm
		501447 LASP1_DROME (274-339): 1.44e-16: 85.6: 34.85		ACT5_DROME (2-375): 0: 596: 95.99
+	Dm
		862562 LASP1_DROME (274-339): 1.44e-16: 85.6: 34.85		ACT3_DROME (2-375): 0: 594: 95.46
+	Dm
		950121 LASP1_DROME (274-339): 1.44e-16: 85.6: 34.85		ACT6_DROME (2-375): 0: 594: 95.99
+	Dm
		361184 LASP1_DROME (274-339): 1.44e-16: 85.6: 34.85		ACT4_DROME (2-375): 0: 589: 94.65