HitPredict

Interactor 1: WDR4 (P57081)
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 (Protein Wuho homolog) (hWH) (WD repeat-containing protein 4)
Gene: WDR4

Interactor 2: RN138 (Q8WVD3)
E3 ubiquitin-protein ligase RNF138 (EC 2.3.2.27) (Nemo-like kinase-associated RING finger protein) (NLK-associated RING finger protein) (hNARF) (RING finger protein 138) (RING-type E3 ubiquitin transferase RNF138)
Gene: RNF138

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 412 Hs			1 245
+	Hs
		1019346 FBXW7_HUMAN (182-378): 7.23e-37: 144: 11.11		TRI26_HUMAN (4-239): 2.73e-33: 127: 15.64
+	Hs
		585027 FBXW7_HUMAN (182-378): 7.23e-37: 144: 11.11		RO52_HUMAN (6-157): 6.92e-32: 123: 17.11
+	Hs
		1281338 FBXW7_HUMAN (182-378): 7.23e-37: 144: 11.11		RING2_HUMAN (2-188): 8.11e-29: 112: 18.72
+	Hs
		1283433 FZR1_HUMAN (28-177): 2.2e-17: 86: 15.48		RN166_HUMAN (5-244): 4.23e-40: 140: 29.58
+	Hs
		1304089 TBL1R_HUMAN (183-378): 2.92e-24: 106: 11.62		RING2_HUMAN (2-188): 8.11e-29: 112: 18.72
+	Mm
		1206589 TBL1R_MOUSE (183-378): 6.51e-24: 105: 11.62		RING2_MOUSE (2-188): 1.78e-28: 112: 18.72
+	Hs
		725534 COPB2_HUMAN (2-128): 1.21e-23: 105: 11.36		RING2_HUMAN (2-188): 8.11e-29: 112: 18.72
+	Hs
		903641 WDR5_HUMAN (282-379): 1.28e-16: 82.1: 12.25		TRAF6_HUMAN (12-245): 1.55e-33: 128: 16.25
+	Hs
		903186 WDR5_HUMAN (282-379): 1.28e-16: 82.1: 12.25		TRAF3_HUMAN (2-245): 1.23e-28: 115: 14.69
+	Hs
		903455 WDR5_HUMAN (282-379): 1.28e-16: 82.1: 12.25		RING2_HUMAN (2-188): 8.11e-29: 112: 18.72
+	Mm
		903677 WDR5_MOUSE (282-379): 1.28e-16: 82.1: 12.25		RING2_MOUSE (2-188): 1.78e-28: 112: 18.72
+	Hs
		903159 WDR5_HUMAN (282-379): 1.28e-16: 82.1: 12.25		RING1_HUMAN (2-74): 3.94e-21: 92.7: 27.40