HitPredict

Interactor 1: WDR4 (P57081)
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 (Protein Wuho homolog) (hWH) (WD repeat-containing protein 4)
Gene: WDR4

Interactor 2: ZMYD8 (Q9ULU4)
MYND-type zinc finger-containing chromatin reader ZMYND8 (Cutaneous T-cell lymphoma-associated antigen se14-3) (CTCL-associated antigen se14-3) (Protein kinase C-binding protein 1) (Rack7) (Transcription coregulator ZMYND8) (Zinc finger MYND domain-containing protein 8)
Gene: ZMYND8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	35914814
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Hs			1 1186
+	Hs
		1281472 FBXW7_HUMAN (182-378): 7.23e-37: 144: 11.11		ZMYD8_HUMAN (1-1186): 0: 1251: 100.00
+	Hs
		987450 FBXW7_HUMAN (182-378): 7.23e-37: 144: 11.11		MTG8_HUMAN (948-1118): 4.47e-49: 187: 20.57
+	Hs
		331862 SNR40_HUMAN (3-128): 1.55e-25: 108: 15.50		NSD2_HUMAN (17-359): 5.44e-55: 212: 17.31
+	Hs
		170444 SNR40_HUMAN (3-128): 1.55e-25: 108: 15.50		TIF1A_HUMAN (38-288): 2.75e-50: 196: 24.44
+	Hs
		1288292 SNR40_HUMAN (3-128): 1.55e-25: 108: 15.50		NSD3_HUMAN (3-359): 2.43e-44: 177: 14.64
+	Hs
		1346965 NLE1_HUMAN (222-379): 1.8e-29: 121: 7.98		BAZ2A_HUMAN (82-251): 2.51e-37: 155: 18.50
+	Hs
		1017466 CDC20_HUMAN (8-172): 1.23e-20: 95.6: 14.86		TRI33_HUMAN (12-288): 1.97e-42: 171: 22.09
+	Hs
		1288369 SNR40_HUMAN (3-128): 1.55e-25: 108: 15.50		BAZ2A_HUMAN (82-251): 2.51e-37: 155: 18.50
+	Hs
		1357192 FZR1_HUMAN (28-177): 2.2e-17: 86: 15.48		TRI33_HUMAN (12-288): 1.97e-42: 171: 22.09
+	Sp
		252179 NLE1_SCHPO (3-172): 3.9e-42: 156: 11.96		YK82_SCHPO (105-249): 2.5e-20: 99.4: 21.09
+	Hs
		600117 WDR5_HUMAN (282-379): 1.28e-16: 82.1: 12.25		TAF1_HUMAN (14-254): 1.28e-24: 114: 20.57
+	Hs
		1017404 CDC20_HUMAN (8-172): 1.23e-20: 95.6: 14.86		PB1_HUMAN (115-379): 7.74e-19: 95.1: 11.57
+	Mm
		1265132 TAF5L_MOUSE (28-163): 3.83e-23: 103: 15.65		KAT2A_MOUSE (142-251): 2.39e-13: 76.9: 27.03
+	Hs
		267783 TAF5L_HUMAN (28-163): 5.97e-23: 102: 16.33		KAT2A_HUMAN (142-251): 1.37e-13: 77.6: 27.03
+	Hs
		267784 TAF5L_HUMAN (28-163): 5.97e-23: 102: 16.33		KAT2B_HUMAN (142-251): 2.88e-13: 76.5: 27.93
+	Hs
		1271467 FZR1_HUMAN (28-177): 2.2e-17: 86: 15.48		KAT2A_HUMAN (142-251): 1.37e-13: 77.6: 27.03
+	Hs
		1271512 FZR1_HUMAN (28-177): 2.2e-17: 86: 15.48		KAT2B_HUMAN (142-251): 2.88e-13: 76.5: 27.93
+	Hs
		903408 WDR5_HUMAN (282-379): 1.28e-16: 82.1: 12.25		KAT2A_HUMAN (142-251): 1.37e-13: 77.6: 27.03
+	Mm
		903679 WDR5_MOUSE (282-379): 1.28e-16: 82.1: 12.25		KAT2A_MOUSE (142-251): 2.39e-13: 76.9: 27.03
+	Hs
		903409 WDR5_HUMAN (282-379): 1.28e-16: 82.1: 12.25		KAT2B_HUMAN (142-251): 2.88e-13: 76.5: 27.93