HitPredict

Interactor 1: LOXL3 (P58215)
Lysyl oxidase homolog 3 (EC 1.4.3.-) (EC 1.4.3.13) (Lysyl oxidase-like protein 3)
Gene: LOXL3

Interactor 2: LTBP1 (Q14766)
Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1)
Gene: LTBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0062023 - collagen-containing extracellular matrix
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 753 Hs			1 1721
+	Hs
		82344 B9A025_HUMAN (1-429): 1.54e-114: 360: 54.34		LTBP1_HUMAN (1-1721): 0: 643: 100.00
+	Hs
		657674 LYOX_HUMAN (525-729): 1.1e-100: 318: 51.21		LTBP1_HUMAN (1-1721): 0: 643: 100.00
+	Hs
		881956 NETR_HUMAN (287-561): 2.83e-59: 217: 31.27		NOTC2_HUMAN (324-1440): 2.5e-70: 265: 14.04
+	Dm
		422950 Q9W2C9_DROME (167-408): 1.36e-55: 200: 30.74		NOTCH_DROME (287-1427): 3.09e-70: 264: 13.21
+	Mm
		957044 LOXL1_MOUSE (500-729): 3.38e-109: 346: 47.46		FBLN5_MOUSE (870-1079): 7.84e-23: 105: 36.40
+	Hs
		995493 LOXL1_HUMAN (500-729): 2.39e-106: 338: 47.46		FBLN5_HUMAN (1094-1313): 2.09e-24: 110: 30.83
+	Hs
		657689 LYOX_HUMAN (525-729): 1.1e-100: 318: 51.21		FBLN5_HUMAN (1094-1313): 2.09e-24: 110: 30.83
+	Hs
		724338 LOXL1_HUMAN (500-729): 2.39e-106: 338: 47.46		FBN1_HUMAN (323-769): 2.93e-10: 67.9: 10.71
+	Hs
		657662 LYOX_HUMAN (525-729): 1.1e-100: 318: 51.21		FBN1_HUMAN (323-769): 2.93e-10: 67.9: 10.71