HitPredict

Interactor 1: H2B1D (P58876)
Histone H2B type 1-D (H2B-clustered histone 5) (HIRA-interacting protein 2) (Histone H2B.1 B) (Histone H2B.b) (H2B/b)
Gene: H2BC5

Interactor 2: MK07 (Q13164)
Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24) (Big MAP kinase 1) (BMK-1) (Extracellular signal-regulated kinase 5) (ERK-5)
Gene: MAPK7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 816
+	Hs
		1026862 H2B2F_HUMAN (1-126): 3.9e-54: 167: 97.62		MK07_HUMAN (1-816): 0: 645: 100.00
+	Hs
		1026875 H2B1M_HUMAN (1-126): 4.45e-54: 167: 96.83		MK07_HUMAN (1-816): 0: 645: 100.00
+	Hs
		1026868 H2B1H_HUMAN (1-126): 8.88e-54: 166: 98.41		MK07_HUMAN (1-816): 0: 645: 100.00
+	Hs
		241518 H2B1K_HUMAN (1-126): 2.11e-53: 165: 98.41		MK07_HUMAN (1-816): 0: 645: 100.00
+	Hs
		883013 H2BFS_HUMAN (1-126): 1.64e-53: 165: 96.83		MK07_HUMAN (1-816): 0: 645: 100.00
+	Hs
		918333 H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21		MK07_HUMAN (1-816): 0: 645: 100.00
+	Hs
		1026874 H2B1N_HUMAN (1-126): 3.49e-53: 164: 99.21		MK07_HUMAN (1-816): 0: 645: 100.00
+	Hs
		1026876 H2B1L_HUMAN (1-126): 3.72e-52: 162: 97.62		MK07_HUMAN (1-816): 0: 645: 100.00
+	Rn
		926453 H2B1_RAT (1-126): 1.23e-50: 158: 96.03		MK01_RAT (41-390): 1.42e-144: 431: 49.43
+	Hs
		625471 H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41		CDK2_HUMAN (52-353): 4.12e-141: 420: 38.16
+	Hs
		625165 H2B1B_HUMAN (1-126): 1.77e-53: 165: 97.62		CDK2_HUMAN (52-353): 4.12e-141: 420: 38.16